A new class EC 7, Translocases, has been added to the EC list. It will be part of ENZYME from release 2018_10. Read more about EC 7 here.
ENZYME entry: EC 2.6.1.95
Accepted Name |
Neomycin C transaminase.
|
Reaction catalysed |
Neomycin C + 2-oxoglutarate <=> 6'''-deamino-6'''-oxoneomycin C + L-glutamate |
Comment(s) |
- The reaction occurs in vivo in the opposite direction.
- Involved in the biosynthetic pathway of aminoglycoside antibiotics of
the neomycin family.
- Works in combination with EC 1.1.3.44 to replace the 6'''-hydroxy
group of 6'''-deamino-6'''-hydroxyneomycin C with an amino group.
- The enzyme, characterized from the bacterium Streptomyces fradiae,
can also catalyze EC 2.6.1.93.
|
Cross-references |
BRENDA | 2.6.1.95 |
EC2PDB | 2.6.1.95 |
ExplorEnz | 2.6.1.95 |
PRIAM enzyme-specific profiles | 2.6.1.95 |
KEGG Ligand Database for Enzyme Nomenclature | 2.6.1.95 |
IUBMB Enzyme Nomenclature | 2.6.1.95 |
IntEnz | 2.6.1.95 |
MEDLINE | Find literature relating to 2.6.1.95 |
MetaCyc | 2.6.1.95 |
UniProtKB/Swiss-Prot |
|
View entry in original ENZYME format
View entry in raw text format (no links)
All
ENZYME /
UniProtKB/Swiss-Prot entries corresponding to 2.6.1.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 2.6.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 2.-.-.-