ENZYME entry: EC 1.14.11.61
Accepted Name |
Feruloyl-CoA 6-hydroxylase.
|
Reaction catalysed |
Trans-feruloyl-CoA + 2-oxoglutarate + O(2) <=> trans-6-hydroxy-feruloyl-CoA + succinate + CO(2) |
Comment(s) |
- Requires iron(II) and ascorbate.
- The product spontaneously undergoes trans-cis isomerization and
lactonization to form scopoletin, liberating CoA in the process.
- The enzymes from the plants Ruta graveolens and Ipomoea batatas also
act on trans-4-coumaroyl-CoA.
- Cf. EC 1.14.11.62.
|
Cross-references |
BRENDA | 1.14.11.61 |
EC2PDB | 1.14.11.61 |
ExplorEnz | 1.14.11.61 |
PRIAM enzyme-specific profiles | 1.14.11.61 |
KEGG Ligand Database for Enzyme Nomenclature | 1.14.11.61 |
IUBMB Enzyme Nomenclature | 1.14.11.61 |
IntEnz | 1.14.11.61 |
MEDLINE | Find literature relating to 1.14.11.61 |
MetaCyc | 1.14.11.61 |
Rhea expert-curated reactions | 1.14.11.61 |
UniProtKB/Swiss-Prot |
A0A023GS28, DIOX1_RUTGR; | A0A023GS29, DIOX2_RUTGR; | W5QJZ5, DIOX4_RUTGR; |
G9M9M0, F6H11_IPOBA; | G9M9M1, F6H12_IPOBA; | G9M9M2, F6H13_IPOBA; |
Q9LHN8, F6H1_ARATH; | G9M9M4, F6H21_IPOBA; | G9M9M3, F6H22_IPOBA; |
G9M9M5, F6H28_IPOBA; | Q9C899, F6H2_ARATH; |
|
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