Home  |  Contact
Due to maintenance work, this service and ftp://ftp.expasy.org will be unavailable from Tuesday August 23rd 18:00 until Wednesday August 24th 08:00 CEST. Apologies for the inconvenience.

ENZYME entry: EC 1.14.13.212

Accepted Name
1,3,7-trimethyluric acid 5-monooxygenase.
Reaction catalysed
1,3,7-trimethylurate + H(+) + NADH + O2 <=> 1,3,7-trimethyl-5-hydroxyisourate + H2O + NAD(+)
Comment(s)
  • The enzyme, characterized from the bacterium Pseudomonas sp. CBB1, is part of the bacterial C-8 oxidation-based caffeine degradation pathway.
  • The product decomposes spontaneously to a racemic mixture of 3,6,8- trimethylallantoin.
  • The enzyme shows no acitivity with urate.
  • Cf. EC 1.14.13.113.
Cross-references
BRENDA1.14.13.212
EC2PDB1.14.13.212
ExplorEnz1.14.13.212
PRIAM enzyme-specific profiles1.14.13.212
KEGG Ligand Database for Enzyme Nomenclature1.14.13.212
IUBMB Enzyme Nomenclature1.14.13.212
IntEnz1.14.13.212
MEDLINEFind literature relating to 1.14.13.212
MetaCyc1.14.13.212
Rhea expert-curated reactions1.14.13.212

View entry in original ENZYME format
View entry in raw text format (no links)
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 1.14.13.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 1.14.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 1.-.-.-