ENZYME entry: EC 1.14.14.23
Accepted Name |
cholesterol 7alpha-monooxygenase.
|
Alternative Name(s) |
cholesterol 7alpha-hydroxylase. |
CYP7A1. |
Reaction catalysed |
cholesterol + O2 + reduced [NADPH--hemoprotein reductase] <=> 7alpha-hydroxycholesterol + H(+) + H2O + oxidized [NADPH--hemoprotein reductase] |
Comment(s) |
- Catalyzes the first step in the biosynthesis of bile acids.
- The direct electron donor to the enzyme is EC 1.6.2.4.
- Formerly EC 1.14.13.17.
|
Cross-references |
BRENDA | 1.14.14.23 |
EC2PDB | 1.14.14.23 |
ExplorEnz | 1.14.14.23 |
PRIAM enzyme-specific profiles | 1.14.14.23 |
KEGG Ligand Database for Enzyme Nomenclature | 1.14.14.23 |
IUBMB Enzyme Nomenclature | 1.14.14.23 |
IntEnz | 1.14.14.23 |
MEDLINE | Find literature relating to 1.14.14.23 |
MetaCyc | 1.14.14.23 |
Rhea expert-curated reactions | 1.14.14.23 |
UniProtKB/Swiss-Prot |
|
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