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ENZYME entry: EC 1.14.14.26
Accepted Name |
24-hydroxycholesterol 7alpha-hydroxylase.
|
Alternative Name(s) |
24-hydroxycholesterol 7alpha-monooxygenase. |
Reaction catalysed |
(24S)-hydroxycholesterol + O2 + reduced [NADPH--hemoprotein reductase] <=> (24S)-7alpha-dihydroxycholesterol + H(+) + H2O + oxidized [NADPH--hemoprotein reductase] |
Comment(s) |
- Found in liver microsomes and in ciliary non-pigmented epithelium.
- Specific for (24S)-cholest-5-ene-3beta,24-diol, which is formed
mostly in the brain by EC 1.14.14.25.
- The direct electron donor to the enzyme is EC 1.6.2.4.
- Formerly EC 1.14.13.99.
|
Cross-references |
BRENDA | 1.14.14.26 |
EC2PDB | 1.14.14.26 |
ExplorEnz | 1.14.14.26 |
PRIAM enzyme-specific profiles | 1.14.14.26 |
KEGG Ligand Database for Enzyme Nomenclature | 1.14.14.26 |
IUBMB Enzyme Nomenclature | 1.14.14.26 |
IntEnz | 1.14.14.26 |
MEDLINE | Find literature relating to 1.14.14.26 |
MetaCyc | 1.14.14.26 |
Rhea expert-curated reactions | 1.14.14.26 |
UniProtKB/Swiss-Prot |
|
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ENZYME /
UniProtKB/Swiss-Prot entries corresponding to 1.14.14.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 1.14.-.-
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