Home  |  Contact

ENZYME entry: EC 1.14.14.77

Accepted Name
Phenylacetonitrile alpha-monooxygenase.
Alternative Name(s)
CYP3201B1.
Reaction catalysed
Phenylacetonitrile + [reduced NADPH--hemoprotein reductase] + O(2) <=> (R)-mandelonitrile + [oxidized NADPH--hemoprotein reductase] + H(2)O
Comment(s)
  • The enzyme has been characterized from the cyanogenic millipede Chamberlinius hualienensis.
  • Unlike plant enzymes that can catalyze this reaction (EC 1.14.14.44), this enzyme cannot act on phenylacetaldehyde oximes.
  • It can accept (4-hydroxyphenyl)acetonitrile, (2-methylphenyl)acetonitrile, and (3-methylphenyl)acetonitrile as substrates at a lower rate.
Cross-references
BRENDA1.14.14.77
EC2PDB1.14.14.77
ExplorEnz1.14.14.77
PRIAM enzyme-specific profiles1.14.14.77
KEGG Ligand Database for Enzyme Nomenclature1.14.14.77
IUBMB Enzyme Nomenclature1.14.14.77
IntEnz1.14.14.77
MEDLINEFind literature relating to 1.14.14.77
MetaCyc1.14.14.77
UniProtKB/Swiss-Prot
A0A068Q609, C7124_PRUMU

View entry in original ENZYME format
View entry in raw text format (no links)
All UniProtKB/Swiss-Prot entries referenced in this entry, with possibility to download in different formats, align etc.
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 1.14.14.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 1.14.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 1.-.-.-