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ENZYME entry: EC 1.14.15.22

Accepted Name
Vitamin D 1,25-hydroxylase.
Alternative Name(s)
CYP105A1.
Reaction catalysed
  • Calciol + O(2) + 2 reduced ferredoxin [iron-sulfur] cluster + 2 H(+) <=> calcidiol + 2 oxidized ferredoxin [iron-sulfur] cluster + H(2)O
  • Calcidiol + 2 reduced ferredoxin [iron-sulfur] cluster + 2 H(+) + O(2) <=> calcitriol + 2 oxidized ferredoxin [iron-sulfur] cluster + H(2)O
Comment(s)
Cross-references
BRENDA1.14.15.22
EC2PDB1.14.15.22
ExplorEnz1.14.15.22
PRIAM enzyme-specific profiles1.14.15.22
KEGG Ligand Database for Enzyme Nomenclature1.14.15.22
IUBMB Enzyme Nomenclature1.14.15.22
IntEnz1.14.15.22
MEDLINEFind literature relating to 1.14.15.22
MetaCyc1.14.15.22
Rhea expert-curated reactions1.14.15.22
UniProtKB/Swiss-Prot
P18326, CPXE_STRGO

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