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ENZYME

ENZYME entry: EC 1.16.1.7

Accepted Name
ferric-chelate reductase (NADH)
Alternative Name(s)
ferric chelate reductase
iron chelate reductase
NADH:Fe(3+)-EDTA reductase
NADH:Fe(3+) oxidoreductase
Reaction catalysed
2 a Fe(II)-siderophore + H(+) + NAD(+) <=> 2 a Fe(III)-siderophore + NADH
Comment(s)
  • The enzyme catalyzes the reduction of bound ferric iron in a variety of iron chelators (siderophores), resulting in the release of ferrous iron.
  • The plant enzyme is involved in the transport of iron across plant plasma membranes.
  • The enzyme from the bacterium Paracoccus denitrificans can also reduce chromate. cf. EC 1.16.1.9 and EC 1.16.1.10.
  • Formerly EC 1.6.99.13.
Cross-references
BRENDA1.16.1.7
EC2PDB1.16.1.7
ExplorEnz1.16.1.7
PRIAM enzyme-specific profiles1.16.1.7
KEGG Ligand Database for Enzyme Nomenclature1.16.1.7
IUBMB Enzyme Nomenclature1.16.1.7
IntEnz1.16.1.7
MEDLINEFind literature relating to 1.16.1.7
MetaCyc1.16.1.7
Rhea expert-curated reactions1.16.1.7
UniProtKB/Swiss-Prot
P84468, FERA_PARDEP84469, FERB_PARDEQ75CQ8, FRE8_EREGS
Q12209, FRE8_YEASTP78588, FREL_CANAXQ9LMM2, FRO1_ARATH
P92949, FRO2_ARATHF4I4K7, FRO3_ARATHQ8W110, FRO4_ARATH
Q9FLW2, FRO5_ARATHQ8RWS6, FRO6_ARATHQ3KTM0, FRO7_ARATH
Q8VY13, FRO8_ARATHA5F660, VIUB_VIBC3P0C6Q2, VIUB_VIBCH
V5XKC3, VUUB_VIBVLQ56743, VUUB_VIBVU

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All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 1.16.1.-
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