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ENZYME

ENZYME entry: EC 1.2.7.3

PURL: https://purl.expasy.org/enzyme/EC/1.2.7.3
Accepted Name
2-oxoglutarate synthase
Alternative Name(s)
2-ketoglutarate ferredoxin oxidoreductase
2-oxoglutarate ferredoxin oxidoreductase
alpha-ketoglutarate-ferredoxin oxidoreductase
alpha-ketoglutarate synthase
KGOR
Reaction catalysed
2 oxidized [2Fe-2S]-[ferredoxin] + 2-oxoglutarate + CoA = succinyl-CoA + 2 reduced [2Fe-2S]-[ferredoxin] + CO2 + H(+)
Comment(s)
  • Highly specific for 2-oxoglutarate.
  • This enzyme is a member of the 2-oxoacid oxidoreductases, a family of enzymes that oxidatively decarboxylate different 2-oxoacids to form their CoA derivatives, and are differentiated based on their substrate specificity.
  • For examples of other members of this family, see EC 1.2.7.1 and EC 1.2.7.7.
  • Formerly EC 1.2.7.9.
Cross-references
BRENDA1.2.7.3
EC2PDB1.2.7.3
ExplorEnz1.2.7.3
KEGG Ligand Database for Enzyme Nomenclature1.2.7.3
IUBMB Enzyme Nomenclature1.2.7.3
MEDLINEFind literature relating to 1.2.7.3
MetaCyc1.2.7.3
Rhea expert-curated reactions1.2.7.3
UniProtKB/Swiss-Prot
O29781, KORA_ARCFUQ57724, KORA_METJAO27112, KORA_METTH
P80904, KORA_METTMO53182, KORA_MYCTUO29782, KORB_ARCFU
Q57957, KORB_METJAO27113, KORB_METTHP80905, KORB_METTM
O53181, KORB_MYCTUO29779, KORC_ARCFUQ57956, KORC_METJA
O27114, KORC_METTHP80906, KORC_METTM

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All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 1.2.7.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 1.2.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 1.-.-.-