ENZYME entry: EC 1.2.7.3
| Accepted Name |
|---|
| 2-oxoglutarate synthase.
|
| Alternative Name(s) |
|---|
| 2-ketoglutarate ferredoxin oxidoreductase. |
| 2-oxoglutarate ferredoxin oxidoreductase. |
| Alpha-ketoglutarate synthase. |
| Alpha-ketoglutarate-ferredoxin oxidoreductase. |
| KGOR. |
| Reaction catalysed |
|---|
| 2-oxoglutarate + CoA + 2 oxidized ferredoxin <=> succinyl-CoA + CO(2) + 2 reduced ferredoxin + 2 H(+) |
| Cofactor(s) |
|---|
| Iron-sulfur; Thiamine diphosphate.
|
| Comment(s) |
|---|
- Highly specific for 2-oxoglutarate.
- This enzyme is a member of the 2-oxoacid oxidoreductases, a family of
enzymes that oxidatively decarboxylate different 2-oxoacids to form
their CoA derivatives, and are differentiated based on their
substrate specificity.
- For examples of other members of this family, see EC 1.2.7.1 and
EC 1.2.7.7.
- Formerly EC 1.2.7.9.
|
| Cross-references |
|---|
| BRENDA | 1.2.7.3 |
| EC2PDB | 1.2.7.3 |
| ExplorEnz | 1.2.7.3 |
| PRIAM enzyme-specific profiles | 1.2.7.3 |
| KEGG Ligand Database for Enzyme Nomenclature | 1.2.7.3 |
| IUBMB Enzyme Nomenclature | 1.2.7.3 |
| IntEnz | 1.2.7.3 |
| MEDLINE | Find literature relating to 1.2.7.3 |
| MetaCyc | 1.2.7.3 |
| UniProtKB/Swiss-Prot |
| O29781, KORA_ARCFU; | Q57724, KORA_METJA; | O27112, KORA_METTH; |
| P80904, KORA_METTM; | O53182, KORA_MYCTU; | O29782, KORB_ARCFU; |
| Q57957, KORB_METJA; | O27113, KORB_METTH; | P80905, KORB_METTM; |
| O53181, KORB_MYCTU; | O29779, KORC_ARCFU; | Q57956, KORC_METJA; |
| O27114, KORC_METTH; | P80906, KORC_METTM; |
|
View entry in original ENZYME format
View entry in raw text format (no links)
All UniProtKB/Swiss-Prot
entries referenced
in this entry, with possibility to download in different formats, align etc.
All
ENZYME /
UniProtKB/Swiss-Prot entries corresponding to 1.2.7.-
All
ENZYME /
UniProtKB/Swiss-Prot entries corresponding to 1.2.-.-
All
ENZYME /
UniProtKB/Swiss-Prot entries corresponding to 1.-.-.-