ENZYME entry: EC 1.2.7.3
Accepted Name |
2-oxoglutarate synthase.
|
Alternative Name(s) |
2-ketoglutarate ferredoxin oxidoreductase. |
2-oxoglutarate ferredoxin oxidoreductase. |
Alpha-ketoglutarate synthase. |
Alpha-ketoglutarate-ferredoxin oxidoreductase. |
KGOR. |
Reaction catalysed |
2-oxoglutarate + CoA + 2 oxidized ferredoxin <=> succinyl-CoA + CO(2) + 2 reduced ferredoxin + 2 H(+) |
Cofactor(s) |
Iron-sulfur; Thiamine diphosphate.
|
Comment(s) |
- Highly specific for 2-oxoglutarate.
- This enzyme is a member of the 2-oxoacid oxidoreductases, a family of
enzymes that oxidatively decarboxylate different 2-oxoacids to form
their CoA derivatives, and are differentiated based on their
substrate specificity.
- For examples of other members of this family, see EC 1.2.7.1 and
EC 1.2.7.7.
- Formerly EC 1.2.7.9.
|
Cross-references |
BRENDA | 1.2.7.3 |
EC2PDB | 1.2.7.3 |
ExplorEnz | 1.2.7.3 |
PRIAM enzyme-specific profiles | 1.2.7.3 |
KEGG Ligand Database for Enzyme Nomenclature | 1.2.7.3 |
IUBMB Enzyme Nomenclature | 1.2.7.3 |
IntEnz | 1.2.7.3 |
MEDLINE | Find literature relating to 1.2.7.3 |
MetaCyc | 1.2.7.3 |
UniProtKB/Swiss-Prot |
O29781, KORA_ARCFU; | Q57724, KORA_METJA; | O27112, KORA_METTH; |
P80904, KORA_METTM; | O53182, KORA_MYCTU; | O29782, KORB_ARCFU; |
Q57957, KORB_METJA; | O27113, KORB_METTH; | P80905, KORB_METTM; |
O53181, KORB_MYCTU; | O29779, KORC_ARCFU; | Q57956, KORC_METJA; |
O27114, KORC_METTH; | P80906, KORC_METTM; |
|
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