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ENZYME

ENZYME entry: EC 1.2.7.8

PURL: https://purl.expasy.org/enzyme/EC/1.2.7.8
Accepted Name
indolepyruvate ferredoxin oxidoreductase
Alternative Name(s)
3-(indol-3-yl)pyruvate synthase (ferredoxin)
IOR
Reaction catalysed
indole-3-pyruvate + 2 oxidized [2Fe-2S]-[ferredoxin] + CoA = (indol-3-yl)acetyl-CoA + 2 reduced [2Fe-2S]-[ferredoxin] + CO2 + H(+)
Comment(s)
  • Preferentially utilizes the transaminated forms of aromatic amino acids and can use phenylpyruvate and 4-hydroxyphenylpyruvate as substrates.
  • This enzyme, which is found in archaea, is a member of the 2-oxoacid oxidoreductases, a family of enzymes that oxidatively decarboxylate different 2-oxoacids to form their CoA derivatives, and are differentiated based on their substrate specificity.
  • For examples of other members of this family, see EC 1.2.7.3 and EC 1.2.7.7.
Cross-references
BRENDA1.2.7.8
EC2PDB1.2.7.8
ExplorEnz1.2.7.8
KEGG Ligand Database for Enzyme Nomenclature1.2.7.8
IUBMB Enzyme Nomenclature1.2.7.8
MEDLINEFind literature relating to 1.2.7.8
MetaCyc1.2.7.8
Rhea expert-curated reactions1.2.7.8
UniProtKB/Swiss-Prot
O28783, IORA_ARCFUO27880, IORA_METTHP80910, IORA_METTM
Q9UZ57, IORA_PYRABO58495, IORA_PYRHOO07835, IORA_THEKO
O28249, IORB_ARCFUO27881, IORB_METTHP80911, IORB_METTM
Q9UZ56, IORB_PYRABO58496, IORB_PYRHOO07836, IORB_THEKO

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All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 1.2.7.-
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