ENZYME entry: EC 1.2.7.8
Accepted Name |
Indolepyruvate ferredoxin oxidoreductase.
|
Alternative Name(s) |
3-(indol-3-yl)pyruvate synthase (ferredoxin). |
IOR. |
Reaction catalysed |
(Indol-3-yl)pyruvate + CoA + 2 oxidized ferredoxin <=> S-2-(indol-3-yl)acetyl-CoA + CO(2) + 2 reduced ferredoxin + H(+) |
Cofactor(s) |
Iron-sulfur; Thiamine diphosphate.
|
Comment(s) |
- Preferentially utilizes the transaminated forms of aromatic amino
acids and can use phenylpyruvate and 4-hydroxyphenylpyruvate as
substrates.
- This enzyme, which is found in archaea, is a member of the 2-oxoacid
oxidoreductases, a family of enzymes that oxidatively decarboxylate
different 2-oxoacids to form their CoA derivatives, and are
differentiated based on their substrate specificity.
- For examples of other members of this family, see EC 1.2.7.3 and
EC 1.2.7.7.
|
Cross-references |
BRENDA | 1.2.7.8 |
EC2PDB | 1.2.7.8 |
ExplorEnz | 1.2.7.8 |
PRIAM enzyme-specific profiles | 1.2.7.8 |
KEGG Ligand Database for Enzyme Nomenclature | 1.2.7.8 |
IUBMB Enzyme Nomenclature | 1.2.7.8 |
IntEnz | 1.2.7.8 |
MEDLINE | Find literature relating to 1.2.7.8 |
MetaCyc | 1.2.7.8 |
Rhea expert-curated reactions | 1.2.7.8 |
UniProtKB/Swiss-Prot |
O28783, IORA_ARCFU; | O27880, IORA_METTH; | P80910, IORA_METTM; |
Q9UZ57, IORA_PYRAB; | O58495, IORA_PYRHO; | O07835, IORA_THEKO; |
O28249, IORB_ARCFU; | O27881, IORB_METTH; | P80911, IORB_METTM; |
Q9UZ56, IORB_PYRAB; | O58496, IORB_PYRHO; | O07836, IORB_THEKO; |
|
View entry in original ENZYME format
View entry in raw text format (no links)
All
ENZYME /
UniProtKB/Swiss-Prot entries corresponding to 1.2.7.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 1.2.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 1.-.-.-