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A new class EC 7, Translocases, has been added to the EC list. It will be part of ENZYME from release 2018_10. Read more about EC 7 here.

ENZYME entry: EC 1.2.98.1

Accepted Name
Formaldehyde dismutase.
Reaction catalysed
2 formaldehyde + H(2)O <=> formate + methanol
Cofactor(s)
Mg(2+); NADP(+) or NAD(+); Zn(2+).
Comment(s)
  • Enzyme-bound NADPH formed by oxidation of formaldehyde to formate is oxidized back to NADP(+) by reaction with a second formaldehyde, yielding methanol.
  • The enzyme from Mycobacterium sp. DSM 3803 also catalyzes the reactions of EC 1.1.99.36 and EC 1.1.99.37.
  • Formaldehyde and acetaldehyde can act as donors; formaldehyde, acetaldehyde and propanal can act as acceptors.
  • Formerly EC 1.2.99.4.
Cross-references
BRENDA1.2.98.1
EC2PDB1.2.98.1
ExplorEnz1.2.98.1
PRIAM enzyme-specific profiles1.2.98.1
KEGG Ligand Database for Enzyme Nomenclature1.2.98.1
IUBMB Enzyme Nomenclature1.2.98.1
IntEnz1.2.98.1
MEDLINEFind literature relating to 1.2.98.1
MetaCyc1.2.98.1
UniProtKB/Swiss-Prot
P46154, FADH_PSEPU;  Q52078, FDM_PSEPU;  

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