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A new class EC 7, Translocases, has been added to the EC list. It will be part of ENZYME from release 2018_10. Read more about EC 7 here.
ENZYME entry: EC 22.214.171.124
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|Acetyl phosphate + methylamine + thioredoxin disulfide + H(2)O <=> N-methylglycine + phosphate + thioredoxin|
- The reaction is observed only in the direction of sarcosine
- The enzyme from Eubacterium acidaminophilum consists of subunits A,
B and C.
- Subunit B contains selenocysteine and a pyruvoyl group, and is
responsible for sarcosine binding and methylamine release.
- Subunit A, which also contains selenocysteine, is reduced by
thioredoxin, and is needed to convert the carboxymethyl group into a
ketene equivalent, in turn used by subunit C to produce acetyl
- Only subunit B distinguishes this enzyme from EC 126.96.36.199 and
|PRIAM enzyme-specific profiles||188.8.131.52|
|KEGG Ligand Database for Enzyme Nomenclature||184.108.40.206|
|IUBMB Enzyme Nomenclature||220.127.116.11|
|MEDLINE||Find literature relating to 18.104.22.168|
|P50972, GRDA1_PEPAC; ||Q6LH20, GRDA1_PHOPR; ||O32518, GRDA2_PEPAC; |
|Q6LH19, GRDA2_PHOPR; ||P26971, GRDA_ACESD; ||A6TU46, GRDA_ALKMQ; |
|Q3A9J5, GRDA_CARHZ; ||A7FTE0, GRDA_CLOB1; ||A7GCV1, GRDA_CLOBL; |
|P26970, GRDA_CLOPU; ||P52216, GRDA_PEPLI; ||Q67KE6, GRDA_SYMTH; |
|Q73PQ2, GRDA_TREDE; ||P54935, GRDC_PEPAC; ||Q47878, GRDD_PEPAC; |
|O86186, GRDF_PEPAC; ||O86185, GRDG_PEPAC; |
entries corresponding to 1.21.4.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 1.21.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 1.-.-.-