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A new class EC 7, Translocases, has been added to the EC list. It will be part of ENZYME from release 2018_10. Read more about EC 7 here.

ENZYME entry: EC

Accepted Name
Anthocyanidin reductase ((2R,3R)-flavan-3-ol-forming).
Alternative Name(s)
Anthocyanidin reductase.
Reaction catalysed
A (2R,3R)-flavan-3-ol + 2 NAD(P)(+) <=> an anthocyanidin with a 3-hydroxy group + 2 NAD(P)H
  • The enzyme participates in the flavonoid biosynthesis pathway found in plants.
  • It catalyzes the double reduction of anthocyanidins, producing (2R,3R)-flavan-3-ol monomers required for the formation of proanthocyanidins.
  • While the enzyme from the legume Medicago truncatula can use both NADPH and NADH as reductant, that from the crucifer Arabidopsis thaliana uses only NADPH.
  • Also, while the substrate preference of the M.truncatula is cyanidin>pelargonidin>delphinidin, the reverse preference is found with the Arabidopsis enzyme.
  • Cf. EC
PRIAM enzyme-specific profiles1.3.1.77
KEGG Ligand Database for Enzyme Nomenclature1.3.1.77
IUBMB Enzyme Nomenclature1.3.1.77
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