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ENZYME entry: EC 1.3.99.28

Accepted Name
phytoene desaturase (neurosporene-forming).
Alternative Name(s)
3-step phytoene desaturase.
Reaction catalysed
15-cis-phytoene + 3 A <=> 3 AH2 + all-trans-neurosporene
Comment(s)
  • This enzyme is involved in carotenoid biosynthesis and catalyzes up to three desaturation steps (cf. EC 1.3.99.29, EC 1.3.99.30, EC 1.3.99.31).
  • The enzyme is activated by FAD.
  • NAD(+), NADP(+) or ATP show no activating effect.
Cross-references
BRENDA1.3.99.28
EC2PDB1.3.99.28
ExplorEnz1.3.99.28
PRIAM enzyme-specific profiles1.3.99.28
KEGG Ligand Database for Enzyme Nomenclature1.3.99.28
IUBMB Enzyme Nomenclature1.3.99.28
IntEnz1.3.99.28
MEDLINEFind literature relating to 1.3.99.28
MetaCyc1.3.99.28
Rhea expert-curated reactions1.3.99.28
UniProtKB/Swiss-Prot
P54980, CRTI_CERS4;  P17054, CRTI_RHOCB;  

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