ENZYME entry: EC 1.8.1.12
Accepted Name |
trypanothione-disulfide reductase.
|
Alternative Name(s) |
N(1),N(8)-bis(glutathionyl)spermidine reductase. |
NADPH:trypanothione oxidoreductase. |
trypanothione reductase. |
Reaction catalysed |
NADP(+) + trypanothione <=> H(+) + NADPH + trypanothione disulfide |
Comment(s) |
- Trypanothione disulfide is the oxidized form of N(1),N(8)-
bis(glutathionyl)-spermidine from the insect-parasitic trypanosomatid
Crithidia fasciculata.
- The activity is dependent on a redox-active cystine at the active
center (cf. EC 1.8.1.7).
- Formerly EC 1.6.4.8.
|
Cross-references |
BRENDA | 1.8.1.12 |
EC2PDB | 1.8.1.12 |
ExplorEnz | 1.8.1.12 |
PRIAM enzyme-specific profiles | 1.8.1.12 |
KEGG Ligand Database for Enzyme Nomenclature | 1.8.1.12 |
IUBMB Enzyme Nomenclature | 1.8.1.12 |
IntEnz | 1.8.1.12 |
MEDLINE | Find literature relating to 1.8.1.12 |
MetaCyc | 1.8.1.12 |
Rhea expert-curated reactions | 1.8.1.12 |
UniProtKB/Swiss-Prot |
|
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