ENZYME entry: EC 2.1.1.246
Accepted Name |
[Methyl-Co(III) methanol-specific corrinoid protein]:coenzyme M
methyltransferase.
|
Reaction catalysed |
A [methyl-Co(III) methanol-specific corrinoid protein] + coenzyme M <=> methyl-CoM + a [Co(I) methanol-specific corrinoid protein] |
Comment(s) |
- The enzyme, which is involved in methanogenesis from methanol,
catalyzes the transfer of a methyl group from a corrinoid protein
(see EC 2.1.1.90), where it is bound to the cobalt cofactor,
to coenzyme M, forming the substrate for EC 2.8.4.1, the enzyme that
catalyzes the final step in methanogenesis.
- Free methylcob(I)alamin can substitute for the corrinoid protein in
vitro.
|
Cross-references |
BRENDA | 2.1.1.246 |
EC2PDB | 2.1.1.246 |
ExplorEnz | 2.1.1.246 |
PRIAM enzyme-specific profiles | 2.1.1.246 |
KEGG Ligand Database for Enzyme Nomenclature | 2.1.1.246 |
IUBMB Enzyme Nomenclature | 2.1.1.246 |
IntEnz | 2.1.1.246 |
MEDLINE | Find literature relating to 2.1.1.246 |
MetaCyc | 2.1.1.246 |
UniProtKB/Swiss-Prot |
|
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