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A new class EC 7, Translocases, has been added to the EC list. It will be part of ENZYME from release 2018_10. Read more about EC 7 here.

ENZYME entry: EC

Accepted Name
[Methyl-Co(III) methanol-specific corrinoid protein]:coenzyme M methyltransferase.
Reaction catalysed
A [methyl-Co(III) methanol-specific corrinoid protein] + coenzyme M <=> methyl-CoM + a [Co(I) methanol-specific corrinoid protein]
  • The enzyme, which is involved in methanogenesis from methanol, catalyzes the transfer of a methyl group from a corrinoid protein (see EC, where it is bound to the cobalt cofactor, to coenzyme M, forming the substrate for EC, the enzyme that catalyzes the final step in methanogenesis.
  • Free methylcob(I)alamin can substitute for the corrinoid protein in vitro.
PRIAM enzyme-specific profiles2.1.1.246
KEGG Ligand Database for Enzyme Nomenclature2.1.1.246
IUBMB Enzyme Nomenclature2.1.1.246
MEDLINEFind literature relating to
Q48927, MTAA_METBA;  Q48949, MTAA_METBF;  

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All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 2.1.1.-
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