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ENZYME entry: EC 2.1.1.378

Accepted Name
[methyl-Co(III) glycine betaine-specific corrinoid protein]- -tetrahydrofolate methyltransferase.
Reaction catalysed
(6S)-5,6,7,8-tetrahydrofolate + methyl-Co(III)-[glycine betaine-specific corrinoid protein] <=> (6S)-5-methyl-5,6,7,8-tetrahydrofolate + Co(I)-[glycine betaine-specific corrinoid protein] + H(+)
Comment(s)
  • This enzyme, characterized from the anaerobic bacterium Desulfitobacterium hafniense Y51, catalyzes a similar reaction to that of EC 2.1.1.258, but in the opposite direction, transferring a methyl group from a methylated corrinoid protein to tetrahydrofolate.
  • The corrinoid protein is specifically methylated by EC 2.1.1.376.
Cross-references
BRENDA2.1.1.378
EC2PDB2.1.1.378
ExplorEnz2.1.1.378
PRIAM enzyme-specific profiles2.1.1.378
KEGG Ligand Database for Enzyme Nomenclature2.1.1.378
IUBMB Enzyme Nomenclature2.1.1.378
IntEnz2.1.1.378
MEDLINEFind literature relating to 2.1.1.378
MetaCyc2.1.1.378
Rhea expert-curated reactions2.1.1.378

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All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 2.1.1.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 2.1.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 2.-.-.-