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A new class EC 7, Translocases, has been added to the EC list. It will be part of ENZYME from release 2018_10. Read more about EC 7 here.

ENZYME entry: EC 2.3.1.217

Accepted Name
Curcumin synthase.
Reaction catalysed
Feruloyl-CoA + feruloylacetyl-CoA + H(2)O <=> 2 CoA + curcumin + CO(2)
Comment(s)
  • A polyketide synthase from the plant Curcuma longa (turmeric).
  • Three isoforms exist, CURS1, CURS2 and CURS3.
  • While CURS1 and CURS2 prefer feruloyl-CoA as a starter substrate, CURS3 can accept 4-coumaroyl-CoA equally well (see EC 2.3.1.219).
Cross-references
BRENDA2.3.1.217
EC2PDB2.3.1.217
ExplorEnz2.3.1.217
PRIAM enzyme-specific profiles2.3.1.217
KEGG Ligand Database for Enzyme Nomenclature2.3.1.217
IUBMB Enzyme Nomenclature2.3.1.217
IntEnz2.3.1.217
MEDLINEFind literature relating to 2.3.1.217
MetaCyc2.3.1.217
UniProtKB/Swiss-Prot
C0SVZ6, CURS1_CURLO;  C6L7V8, CURS2_CURLO;  C6L7V9, CURS3_CURLO;  

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All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 2.3.1.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 2.3.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 2.-.-.-