Expasy logo

ENZYME

ENZYME entry: EC 2.3.1.219

Accepted Name
demethoxycurcumin synthase
Reaction catalysed
  • (E)-4-coumaroyl-CoA + (E)-feruloylacetyl-CoA + H2O <=> CO2 + 2 CoA + demethoxycurcumin
  • (4-coumaroyl)acetyl-CoA + 4-coumaroyl-CoA + H2O <=> bisdemethoxycurcumin + CO2 + 2 CoA
Comment(s)
  • A polyketide synthase from the plant Curcuma longa (turmeric).
  • Three isoforms exist, CURS1, CURS2 and CURS3.
  • While CURS1 and CURS2 prefer feruloyl-CoA as a starter substrate (cf. EC 2.3.1.217), CURS3 can accept 4-coumaroyl-CoA equally well.
Cross-references
BRENDA2.3.1.219
EC2PDB2.3.1.219
ExplorEnz2.3.1.219
PRIAM enzyme-specific profiles2.3.1.219
KEGG Ligand Database for Enzyme Nomenclature2.3.1.219
IUBMB Enzyme Nomenclature2.3.1.219
IntEnz2.3.1.219
MEDLINEFind literature relating to 2.3.1.219
MetaCyc2.3.1.219
Rhea expert-curated reactions2.3.1.219
UniProtKB/Swiss-Prot
C6L7V9, CURS3_CURLO

View entry in original ENZYME format
View entry in raw text format (no links)
All UniProtKB/Swiss-Prot entries referenced in this entry, with possibility to download in different formats, align etc.
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 2.3.1.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 2.3.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 2.-.-.-