A new class EC 7, Translocases, has been added to the EC list. It will be part of ENZYME from release 2018_10. Read more about EC 7 here.
ENZYME entry: EC 188.8.131.52
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|Bile acid-CoA:amino acid N-acyltransferase.
|Amino acid N-choloyltransferase.|
|Cholyl-CoA glycine-taurine N-acyltransferase.|
|Choloyl-CoA + glycine <=> CoA + glycocholate|
- Also acts on CoA derivatives of other bile acids.
- Taurine and 2-fluoro-beta-alanine can act as substrates, but more
- Can also conjugate fatty acids to glycine and can act as a very-long-
chain acyl-CoA thioesterase.
- Bile-acid--amino-acid conjugates serve as detergents in the
gastrointestinal tract, solubilizing long chain fatty acids, mono-
and diglycerides, fat-soluble vitamins and cholesterol.
- This is the second enzyme in a two-step process leading to the
conjugation of bile acids with amino acids; the first step is the
conversion of bile acids into their acyl-CoA thioesters, which is
catalyzed by EC 184.108.40.206.
|PRIAM enzyme-specific profiles||220.127.116.11|
|KEGG Ligand Database for Enzyme Nomenclature||18.104.22.168|
|IUBMB Enzyme Nomenclature||22.214.171.124|
|MEDLINE||Find literature relating to 126.96.36.199|
entries corresponding to 2.3.1.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 2.3.-.-
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