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ENZYME entry: EC 2.4.1.85

Accepted Name
Cyanohydrin beta-glucosyltransferase.
Alternative Name(s)
UDP-glucose-p-hydroxymandelonitrile glucosyltransferase.
UGT85B1.
Uridine diphosphoglucose-cyanohydrin glucosyltransferase.
Uridine diphosphoglucose-p-hydroxymandelonitrile glucosyltransferase.
Reaction catalysed
UDP-alpha-D-glucose + (S)-4-hydroxymandelonitrile <=> UDP + (S)-4-hydroxymandelonitrile beta-D-glucoside
Comment(s)
  • Acts on a wide range of substrates in vitro, including cyanohydrins, terpenoids, phenolics, hexanol derivatives and plant hormones, in a regiospecific manner.
  • Involved in the biosynthesis of the cyanogenic glucoside dhurrin in sorghum, along with EC 1.14.14.36 and EC 1.14.14.37.
  • This reaction prevents the disocciation and release of toxic hydrogen cyanide.
Cross-references
BRENDA2.4.1.85
EC2PDB2.4.1.85
ExplorEnz2.4.1.85
PRIAM enzyme-specific profiles2.4.1.85
KEGG Ligand Database for Enzyme Nomenclature2.4.1.85
IUBMB Enzyme Nomenclature2.4.1.85
IntEnz2.4.1.85
MEDLINEFind literature relating to 2.4.1.85
MetaCyc2.4.1.85
UniProtKB/Swiss-Prot
Q9SBL1, HMNGT_SORBI

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