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A new class EC 7, Translocases, has been added to the EC list. It will be part of ENZYME from release 2018_10. Read more about EC 7 here.
ENZYME entry: EC 22.214.171.124
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|Archaeal oligosaccharyl transferase.|
|An archaeal dolichyl phosphooligosaccharide + [protein]-L-asparagine <=> an archaeal dolichyl phosphate + a glycoprotein with the oligosaccharide chain attached by N-beta-D-glycosyl linkage to a protein L-asparagine|
- The enzyme, characterized from the archaea Methanococcus voltae and
Haloferax volcanii, transfers a glycan component from dolichyl
phosphooligosaccharide to external proteins.
- It is different from EC 126.96.36.199 which uses dolichyl diphosphate as
carrier compound in bacteria and eukaryotes.
- The enzyme participates in the N-glycosylation of proteins in some
- Dolichol used by archaea is different from that used by eukaryotes;
it is much shorter (C(55)-C(60)), it is alpha,omega-saturated and it
may have additional unsaturated positions in the chain.
|PRIAM enzyme-specific profiles||188.8.131.52|
|KEGG Ligand Database for Enzyme Nomenclature||184.108.40.206|
|IUBMB Enzyme Nomenclature||220.127.116.11|
|MEDLINE||Find literature relating to 18.104.22.168|
|O29918, AGLB1_ARCFU; ||Q8U4D2, AGLB1_PYRFU; ||O74088, AGLB1_PYRHO; |
|O30195, AGLB2_ARCFU; ||Q8U3P6, AGLB2_PYRFU; ||O58981, AGLB2_PYRHO; |
|O29867, AGLB3_ARCFU; ||D4GYH4, AGLB_HALVD; ||Q58920, AGLB_METJA; |
|Q2EMT4, AGLB_METVO; |
entries corresponding to 2.4.99.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 2.4.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 2.-.-.-