ENZYME entry: EC 2.5.1.49
Accepted Name |
O-acetylhomoserine aminocarboxypropyltransferase.
|
Alternative Name(s) |
Methionine synthase. |
O-acetyl-L-homoserine acetate-lyase (adding methanethiol). |
O-acetyl-L-homoserine sulfhydrolase. |
O-acetylhomoserine (thiol)-lyase. |
O-acetylhomoserine sulfhydrolase. |
OAH sulfhydrylase. |
Reaction catalysed |
O-acetyl-L-homoserine + methanethiol <=> L-methionine + acetate |
Comment(s) |
- Also reacts with other thiols and H(2)S, producing homocysteine or
thioethers.
- The name methionine synthase is more commonly applied to EC 2.1.1.13.
- The enzyme from Saccharomyces cerevisiae also catalyzes the reaction
of EC 2.5.1.47, but more slowly.
- Formerly EC 4.2.99.10.
|
Cross-references |
PROSITE | PDOC00677 |
BRENDA | 2.5.1.49 |
EC2PDB | 2.5.1.49 |
ExplorEnz | 2.5.1.49 |
PRIAM enzyme-specific profiles | 2.5.1.49 |
KEGG Ligand Database for Enzyme Nomenclature | 2.5.1.49 |
IUBMB Enzyme Nomenclature | 2.5.1.49 |
IntEnz | 2.5.1.49 |
MEDLINE | Find literature relating to 2.5.1.49 |
MetaCyc | 2.5.1.49 |
UniProtKB/Swiss-Prot |
|
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ENZYME /
UniProtKB/Swiss-Prot entries corresponding to 2.5.1.-
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