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ENZYME entry: EC 188.8.131.52
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|lactose PTS permease.|
|lactose(out) + N(pros)-phospho-L-histidyl-[protein] <=> L-histidyl-[protein] + lactose 6-phosphate(in)|
- This enzyme is a component (known as enzyme II) of a
phosphoenolpyruvate (PEP)-dependent, sugar transporting
phosphotransferase system (PTS).
- The system, which is found only in prokaryotes, simultaneously
transports its substrate from the periplasm or extracellular space
into the cytoplasm and phosphorylates it.
- The phosphate donor, which is shared among the different systems,
is a phospho-carrier protein of low molecular mass that has been
phosphorylated by EC 184.108.40.206.
- Enzyme II, on the other hand, is specific for a particular substrate,
although in some cases alternative substrates can be transported with
- The reaction involves a successive transfer of the phosphate group to
several amino acids within the enzyme before the final transfer to
- Formerly EC 220.127.116.11.
|PRIAM enzyme-specific profiles||18.104.22.168|
|KEGG Ligand Database for Enzyme Nomenclature||22.214.171.124|
|IUBMB Enzyme Nomenclature||126.96.36.199|
|MEDLINE||Find literature relating to 188.8.131.52|
|Rhea expert-curated reactions||184.108.40.206|
|P24400, PTLCB_LACCA; ||P23531, PTLCB_LACLL; ||Q5HE15, PTLCB_STAAC; |
|Q931G6, PTLCB_STAAM; ||Q99S77, PTLCB_STAAN; ||Q6GEN9, PTLCB_STAAR; |
|Q6G7C4, PTLCB_STAAS; ||P11162, PTLCB_STAAU; ||Q7A092, PTLCB_STAAW; |
|Q5HM40, PTLCB_STAEQ; ||Q8CNF7, PTLCB_STAES; ||Q4L869, PTLCB_STAHJ; |
|P50976, PTLCB_STRMU; |
entries corresponding to 2.7.1.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 2.7.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 2.-.-.-