ENZYME entry: EC 2.7.1.207
Accepted Name |
protein-N(pi)-phosphohistidine--lactose phosphotransferase.
|
Alternative Name(s) |
lactose PTS permease. |
Reaction catalysed |
lactose(out) + N(pros)-phospho-L-histidyl-[protein] <=> L-histidyl-[protein] + lactose 6-phosphate(in) |
Comment(s) |
- This enzyme is a component (known as enzyme II) of a
phosphoenolpyruvate (PEP)-dependent, sugar transporting
phosphotransferase system (PTS).
- The system, which is found only in prokaryotes, simultaneously
transports its substrate from the periplasm or extracellular space
into the cytoplasm and phosphorylates it.
- The phosphate donor, which is shared among the different systems,
is a phospho-carrier protein of low molecular mass that has been
phosphorylated by EC 2.7.3.9.
- Enzyme II, on the other hand, is specific for a particular substrate,
although in some cases alternative substrates can be transported with
lower efficiency.
- The reaction involves a successive transfer of the phosphate group to
several amino acids within the enzyme before the final transfer to
the substrate.
- Formerly EC 2.7.1.69.
|
Cross-references |
BRENDA | 2.7.1.207 |
EC2PDB | 2.7.1.207 |
ExplorEnz | 2.7.1.207 |
PRIAM enzyme-specific profiles | 2.7.1.207 |
KEGG Ligand Database for Enzyme Nomenclature | 2.7.1.207 |
IUBMB Enzyme Nomenclature | 2.7.1.207 |
IntEnz | 2.7.1.207 |
MEDLINE | Find literature relating to 2.7.1.207 |
MetaCyc | 2.7.1.207 |
Rhea expert-curated reactions | 2.7.1.207 |
UniProtKB/Swiss-Prot |
P24400, PTLCB_LACCA; | P23531, PTLCB_LACLL; | Q5HE15, PTLCB_STAAC; |
Q931G6, PTLCB_STAAM; | Q99S77, PTLCB_STAAN; | Q6GEN9, PTLCB_STAAR; |
Q6G7C4, PTLCB_STAAS; | P11162, PTLCB_STAAU; | Q7A092, PTLCB_STAAW; |
Q5HM40, PTLCB_STAEQ; | Q8CNF7, PTLCB_STAES; | Q4L869, PTLCB_STAHJ; |
P50976, PTLCB_STRMU; |
|
View entry in original ENZYME format
View entry in raw text format (no links)
All
ENZYME /
UniProtKB/Swiss-Prot entries corresponding to 2.7.1.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 2.7.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 2.-.-.-