Expasy logo

ENZYME

ENZYME entry: EC 2.7.11.15

PURL: https://purl.expasy.org/enzyme/EC/2.7.11.15
Accepted Name
[beta-adrenergic-receptor] kinase
Alternative Name(s)
ADRBK1
adrenergic receptor kinase
BARK1
beta2ARK
beta-adrenergic-receptor kinase
beta-adrenergic-receptor kinase (phosphorylating)
beta-adrenergic receptor-specific kinase
beta-adrenoceptor kinase
beta-ARK
beta-AR kinase
beta-receptor kinase
Reaction catalysed
[beta-adrenergic receptor] + ATP = [beta-adrenergic receptor]-phosphate + ADP + H(+)
Comment(s)
  • Acts on the agonist-occupied form of the receptor; also phosphorylates rhodopsin, but more slowly.
  • Does not act on casein or histones.
  • Inhibited by Zn(2+) and digitonin but is unaffected by cyclic-AMP (cf. EC 2.7.11.14 and EC 2.7.11.16).
  • Formerly EC 2.7.1.126.
Cross-references
Rhea expert-curated reactions2.7.11.15
ExplorEnz2.7.11.15
IUBMB Enzyme Nomenclature2.7.11.15
UniProtKB/Swiss-Prot
P21146, ARBK1_BOVINO97627, ARBK1_DIDVIP25098, ARBK1_HUMAN
Q64682, ARBK1_MESAUQ99MK8, ARBK1_MOUSEP26817, ARBK1_RAT
P26818, ARBK2_BOVINP35626, ARBK2_HUMANQ3UYH7, ARBK2_MOUSE
P26819, ARBK2_RAT
BRENDA2.7.11.15
MetaCyc2.7.11.15
KEGG Ligand Database for Enzyme Nomenclature2.7.11.15
EC2PDB2.7.11.15
MEDLINEFind literature relating to 2.7.11.15

View entry in original ENZYME format
View entry in raw text format (no links)
All UniProtKB/Swiss-Prot entries referenced in this entry, with possibility to download in different formats, align etc.
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 2.7.11.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 2.7.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 2.-.-.-