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ENZYME

ENZYME entry: EC 2.7.11.16

Accepted Name
[G-protein-coupled receptor] kinase
Alternative Name(s)
GPCRK
GPCR kinase
G protein-coupled receptor kinase
Reaction catalysed
[G-protein-coupled receptor] + ATP <=> [G-protein-coupled receptor]-phosphate + ADP + H(+)
Comment(s)
  • All members of this enzyme subfamily possess a highly conserved binding site for 1-phosphatidylinositol 4,5-bisphosphate.
  • (cf. EC 2.7.11.14 and EC 2.7.11.15).
Cross-references
BRENDA2.7.11.16
EC2PDB2.7.11.16
ExplorEnz2.7.11.16
PRIAM enzyme-specific profiles2.7.11.16
KEGG Ligand Database for Enzyme Nomenclature2.7.11.16
IUBMB Enzyme Nomenclature2.7.11.16
IntEnz2.7.11.16
MEDLINEFind literature relating to 2.7.11.16
MetaCyc2.7.11.16
Rhea expert-curated reactions2.7.11.16
UniProtKB/Swiss-Prot
P32865, GPRK1_DROMEP32866, GPRK2_DROMEQ622Z7, GRK1_CAEBR
Q09537, GRK1_CAEELQ09639, GRK2_CAEELP32298, GRK4_HUMAN
O70291, GRK4_MOUSEP70507, GRK4_RATP43249, GRK5_BOVIN
P34947, GRK5_HUMANQ8VEB1, GRK5_MOUSEQ62833, GRK5_RAT
P43250, GRK6_HUMANO70293, GRK6_MOUSEP97711, GRK6_RAT

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All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 2.7.11.-
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