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ENZYME

ENZYME entry: EC 2.7.11.16

PURL: https://purl.expasy.org/enzyme/EC/2.7.11.16
Accepted Name
[G-protein-coupled receptor] kinase
Alternative Name(s)
GPCRK
GPCR kinase
G protein-coupled receptor kinase
Reaction catalysed
[G protein-coupled receptor] + ATP = [G protein-coupled receptor]-phosphate + ADP + H(+)
Comment(s)
  • All members of this enzyme subfamily possess a highly conserved binding site for 1-phosphatidylinositol 4,5-bisphosphate.
  • (cf. EC 2.7.11.14 and EC 2.7.11.15).
Cross-references
Rhea expert-curated reactions2.7.11.16
ExplorEnz2.7.11.16
IUBMB Enzyme Nomenclature2.7.11.16
UniProtKB/Swiss-Prot
P32865, GPRK1_DROMEP32866, GPRK2_DROMEQ622Z7, GRK1_CAEBR
Q09537, GRK1_CAEELP21146, GRK2_BOVINQ09639, GRK2_CAEEL
O97627, GRK2_DIDVIP25098, GRK2_HUMANQ64682, GRK2_MESAU
Q99MK8, GRK2_MOUSEP26817, GRK2_RATP26818, GRK3_BOVIN
P35626, GRK3_HUMANQ3UYH7, GRK3_MOUSEP26819, GRK3_RAT
P32298, GRK4_HUMANO70291, GRK4_MOUSEP70507, GRK4_RAT
P43249, GRK5_BOVINP34947, GRK5_HUMANQ8VEB1, GRK5_MOUSE
Q62833, GRK5_RATP43250, GRK6_HUMANO70293, GRK6_MOUSE
P97711, GRK6_RAT
BRENDA2.7.11.16
MetaCyc2.7.11.16
KEGG Ligand Database for Enzyme Nomenclature2.7.11.16
EC2PDB2.7.11.16
MEDLINEFind literature relating to 2.7.11.16

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