ENZYME entry: EC 2.7.11.16
Accepted Name |
[G-protein-coupled receptor] kinase.
|
Alternative Name(s) |
G protein-coupled receptor kinase. |
GPCR kinase. |
GPCRK. |
Reaction catalysed |
ATP + [G-protein-coupled receptor] <=> ADP + [G-protein-coupled receptor] phosphate |
Comment(s) |
- All members of this enzyme subfamily possess a highly conserved
binding site for 1-phosphatidylinositol 4,5-bisphosphate.
- (cf. EC 2.7.11.14 and EC 2.7.11.15).
|
Cross-references |
PROSITE | PDOC00100 |
BRENDA | 2.7.11.16 |
EC2PDB | 2.7.11.16 |
ExplorEnz | 2.7.11.16 |
PRIAM enzyme-specific profiles | 2.7.11.16 |
KEGG Ligand Database for Enzyme Nomenclature | 2.7.11.16 |
IUBMB Enzyme Nomenclature | 2.7.11.16 |
IntEnz | 2.7.11.16 |
MEDLINE | Find literature relating to 2.7.11.16 |
MetaCyc | 2.7.11.16 |
Rhea expert-curated reactions | 2.7.11.16 |
UniProtKB/Swiss-Prot |
P32865, GPRK1_DROME; | P32866, GPRK2_DROME; | Q622Z7, GRK1_CAEBR; |
Q09537, GRK1_CAEEL; | Q09639, GRK2_CAEEL; | P32298, GRK4_HUMAN; |
O70291, GRK4_MOUSE; | P70507, GRK4_RAT; | P43249, GRK5_BOVIN; |
P34947, GRK5_HUMAN; | Q8VEB1, GRK5_MOUSE; | Q62833, GRK5_RAT; |
P43250, GRK6_HUMAN; | O70293, GRK6_MOUSE; | P97711, GRK6_RAT; |
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UniProtKB/Swiss-Prot entries corresponding to 2.7.11.-
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