A new class EC 7, Translocases, has been added to the EC list. It will be part of ENZYME from release 2018_10. Read more about EC 7 here.
ENZYME entry: EC 2.7.11.16
| Accepted Name |
|---|
| [G-protein-coupled receptor] kinase.
|
| Alternative Name(s) |
|---|
| G protein-coupled receptor kinase. |
| GPCR kinase. |
| GPCRK. |
| Reaction catalysed |
|---|
| ATP + [G-protein-coupled receptor] <=> ADP + [G-protein-coupled receptor] phosphate |
| Comment(s) |
|---|
- All members of this enzyme subfamily possess a highly conserved
binding site for 1-phosphatidylinositol 4,5-bisphosphate.
- (cf. EC 2.7.11.14 and EC 2.7.11.15).
|
| Cross-references |
|---|
| PROSITE | PDOC00100 |
| BRENDA | 2.7.11.16 |
| EC2PDB | 2.7.11.16 |
| ExplorEnz | 2.7.11.16 |
| PRIAM enzyme-specific profiles | 2.7.11.16 |
| KEGG Ligand Database for Enzyme Nomenclature | 2.7.11.16 |
| IUBMB Enzyme Nomenclature | 2.7.11.16 |
| IntEnz | 2.7.11.16 |
| MEDLINE | Find literature relating to 2.7.11.16 |
| MetaCyc | 2.7.11.16 |
| UniProtKB/Swiss-Prot |
| P32865, GPRK1_DROME; | P32866, GPRK2_DROME; | Q622Z7, GRK1_CAEBR; |
| Q09537, GRK1_CAEEL; | Q09639, GRK2_CAEEL; | P32298, GRK4_HUMAN; |
| O70291, GRK4_MOUSE; | P70507, GRK4_RAT; | P43249, GRK5_BOVIN; |
| P34947, GRK5_HUMAN; | Q8VEB1, GRK5_MOUSE; | Q62833, GRK5_RAT; |
| P43250, GRK6_HUMAN; | O70293, GRK6_MOUSE; | P97711, GRK6_RAT; |
|
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