ENZYME entry: EC 2.7.7.66
| Accepted Name |
|---|
| Malonate decarboxylase holo-[acyl-carrier protein] synthase.
|
| Alternative Name(s) |
|---|
| Holo ACP synthase. |
| Holo-malonate-decarboxylase synthase. |
| Reaction catalysed |
|---|
| 2'-(5-triphosphoribosyl)-3'-dephospho-CoA + malonate decarboxylase apo-[acyl-carrier protein] <=> malonate decarboxylase holo-[acyl-carrier protein] + diphosphate |
| Comment(s) |
|---|
- The delta subunit of malonate decarboxylase serves as an an acyl-
carrier protein (ACP) and contains the prosthetic group
2'-(5-triphosphoribosyl)-3'-dephospho-CoA.
- Two reactions are involved in the production of the holo-ACP form of
this enzyme.
- The first reaction is catalyzed by EC 2.4.2.52.
- The resulting prosthetic group is then attached to the ACP subunit
via a phosphodiester linkage to a serine residue, thus forming the
holo form of the enzyme, in a manner analogous to that of
EC 2.7.7.61.
|
| Cross-references |
|---|
| BRENDA | 2.7.7.66 |
| EC2PDB | 2.7.7.66 |
| ExplorEnz | 2.7.7.66 |
| PRIAM enzyme-specific profiles | 2.7.7.66 |
| KEGG Ligand Database for Enzyme Nomenclature | 2.7.7.66 |
| IUBMB Enzyme Nomenclature | 2.7.7.66 |
| IntEnz | 2.7.7.66 |
| MEDLINE | Find literature relating to 2.7.7.66 |
| MetaCyc | 2.7.7.66 |
| UniProtKB/Swiss-Prot |
| C1DNP9, MDCG_AZOVD; | Q89XP2, MDCG_BRADU; | B5XRA3, MDCG_KLEP3; |
| A6T8R9, MDCG_KLEP7; | P71426, MDCG_KLEPN; | Q9I6S5, MDCG_PSEAE; |
| Q4K4G0, MDCG_PSEF5; | Q3K5C0, MDCG_PSEPF; | B0KQS7, MDCG_PSEPG; |
| Q9Z448, MDCG_PSEPU; | B1J9E4, MDCG_PSEPW; | Q87V59, MDCG_PSESM; |
| Q8PPW9, MDCG_XANAC; | Q3BY34, MDCG_XANC5; | Q4UZ66, MDCG_XANC8; |
| B0RN93, MDCG_XANCB; | Q8P4U3, MDCG_XANCP; |
|
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