ENZYME entry: EC 3.1.3.76
Accepted Name |
Lipid-phosphate phosphatase.
|
Alternative Name(s) |
Dihydroxy fatty acid phosphatase. |
Hydroxy fatty acid phosphatase. |
Hydroxy lipid phosphatase. |
Soluble epoxide hydrolase. |
Reaction catalysed |
(9S,10S)-10-hydroxy-9-(phosphonooxy)octadecanoate + H(2)O <=> (9S,10S)-9,10-dihydroxyoctadecanoate + phosphate |
Cofactor(s) |
Mg(2+).
|
Comment(s) |
- The enzyme from mammals is a bifunctional enzyme: the N-terminal
domain exhibits lipid-phosphate-phosphatase activity and the
C-terminal domain has the activity of EC 3.3.2.10.
- The best substrates for this enzyme are 10-hydroxy-9-
(phosphonooxy)octadecanoates, with the threo- form being a better
substrate than the erythro- form.
- The phosphatase activity is not found in plant EC 3.3.2.10 or in
mammalian EC 3.3.2.9.
|
Cross-references |
BRENDA | 3.1.3.76 |
EC2PDB | 3.1.3.76 |
ExplorEnz | 3.1.3.76 |
PRIAM enzyme-specific profiles | 3.1.3.76 |
KEGG Ligand Database for Enzyme Nomenclature | 3.1.3.76 |
IUBMB Enzyme Nomenclature | 3.1.3.76 |
IntEnz | 3.1.3.76 |
MEDLINE | Find literature relating to 3.1.3.76 |
MetaCyc | 3.1.3.76 |
UniProtKB/Swiss-Prot |
|
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