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ENZYME

ENZYME entry: EC 3.1.3.76

PURL: https://purl.expasy.org/enzyme/EC/3.1.3.76
Accepted Name
lipid-phosphate phosphatase
Alternative Name(s)
dihydroxy fatty acid phosphatase
hydroxy fatty acid phosphatase
hydroxy lipid phosphatase
soluble epoxide hydrolase
Reaction catalysed
(9S,10S)-10-hydroxy-9-(phosphooxy)octadecanoate + H2O = (9S,10S)-9,10-dihydroxyoctadecanoate + phosphate
Comment(s)
  • The enzyme from mammals is a bifunctional enzyme: the N-terminal domain exhibits lipid-phosphate-phosphatase activity and the C-terminal domain has the activity of EC 3.3.2.10.
  • The best substrates for this enzyme are 10-hydroxy-9- (phosphonooxy)octadecanoates, with the threo- form being a better substrate than the erythro- form.
  • The phosphatase activity is not found in plant EC 3.3.2.10 or in mammalian EC 3.3.2.9.
Cross-references
BRENDA3.1.3.76
EC2PDB3.1.3.76
ExplorEnz3.1.3.76
KEGG Ligand Database for Enzyme Nomenclature3.1.3.76
IUBMB Enzyme Nomenclature3.1.3.76
MEDLINEFind literature relating to 3.1.3.76
MetaCyc3.1.3.76
Rhea expert-curated reactions3.1.3.76
UniProtKB/Swiss-Prot
P34913, HYES_HUMANP34914, HYES_MOUSEQ6Q2C2, HYES_PIG
P80299, HYES_RAT

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