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ENZYME entry: EC 3.1.3.80

Accepted Name
2,3-bisphosphoglycerate 3-phosphatase.
Alternative Name(s)
2,3-BPG 3-phosphatase.
Reaction catalysed
2,3-bisphospho-D-glycerate + H(2)O <=> 2-phospho-D-glycerate + phosphate
Comment(s)
  • This reaction is a shortcut in the Rapoport-Luebering shunt.
  • It bypasses the reactions of EC 5.4.2.11/EC 5.4.2.12 and directly forms 2-phospho-Dglycerate by removing the 3-phospho-group of 2,3- diphospho-Dglycerate.
  • The MIPP1 protein also catalyzes the reaction of EC 3.1.3.62.
Cross-references
PROSITEPDOC00538
BRENDA3.1.3.80
EC2PDB3.1.3.80
ExplorEnz3.1.3.80
PRIAM enzyme-specific profiles3.1.3.80
KEGG Ligand Database for Enzyme Nomenclature3.1.3.80
IUBMB Enzyme Nomenclature3.1.3.80
IntEnz3.1.3.80
MEDLINEFind literature relating to 3.1.3.80
MetaCyc3.1.3.80
Rhea expert-curated reactions3.1.3.80
UniProtKB/Swiss-Prot
F1NPQ2, MINP1_CHICK;  Q54ND5, MINP1_DICDI;  Q9VV72, MINP1_DROME;  
Q9UNW1, MINP1_HUMAN;  Q9Z2L6, MINP1_MOUSE;  Q5R890, MINP1_PONAB;  
O35217, MINP1_RAT;  

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