ENZYME entry: EC 3.1.4.60
| Accepted Name |
|---|
| pApA phosphodiesterase.
|
| Alternative Name(s) |
|---|
| pApA hydrolase. |
| Reaction catalysed |
|---|
| 5'-O-phosphonoadenylyl-(3'->5')-adenosine + H2O <=> 2 AMP + H(+) |
| Comment(s) |
|---|
- The enzyme, characterized from the Gram-positive bacterium
Staphylococcus aureus, is a cytoplasmic protein that contains a
DHH/DHHA1 domain.
- It can act on cyclic di-3',5'-adenylate with a much lower activity
(cf. EC 3.1.4.59).
- Activity requires Mn(2+) and is inhibited by ppGpp.
|
| Cross-references |
|---|
| BRENDA | 3.1.4.60 |
| EC2PDB | 3.1.4.60 |
| ExplorEnz | 3.1.4.60 |
| PRIAM enzyme-specific profiles | 3.1.4.60 |
| KEGG Ligand Database for Enzyme Nomenclature | 3.1.4.60 |
| IUBMB Enzyme Nomenclature | 3.1.4.60 |
| IntEnz | 3.1.4.60 |
| MEDLINE | Find literature relating to 3.1.4.60 |
| MetaCyc | 3.1.4.60 |
| Rhea expert-curated reactions | 3.1.4.60 |
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ENZYME /
UniProtKB/Swiss-Prot entries corresponding to 3.1.4.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 3.1.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 3.-.-.-