ENZYME entry: EC 3.4.21.42
Accepted Name |
Complement subcomponent C1s.
|
Alternative Name(s) |
C1s esterase. |
Reaction catalysed |
Cleavage of Arg-|-Ala bond in complement component C4 to form C4a and C4b, and Lys(or Arg)-|-Lys bond in complement component C2 to form C2a and C2b: the 'classical' pathway C3 convertase |
Comment(s) |
- Activated from proenzyme C1s in plasma by the activated complement
subcomponent C1r.
- Belongs to peptidase family S1.
|
Cross-references |
PROSITE | PDOC00124 |
BRENDA | 3.4.21.42 |
EC2PDB | 3.4.21.42 |
ExplorEnz | 3.4.21.42 |
PRIAM enzyme-specific profiles | 3.4.21.42 |
KEGG Ligand Database for Enzyme Nomenclature | 3.4.21.42 |
IUBMB Enzyme Nomenclature | 3.4.21.42 |
IntEnz | 3.4.21.42 |
MEDLINE | Find literature relating to 3.4.21.42 |
MetaCyc | 3.4.21.42 |
Rhea expert-curated reactions | 3.4.21.42 |
UniProtKB/Swiss-Prot |
|
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