A new class EC 7, Translocases, has been added to the EC list. It will be part of ENZYME from release 2018_10. Read more about EC 7 here.
ENZYME entry: EC 3.4.21.42
| Accepted Name |
|---|
| Complement subcomponent C1s.
|
| Alternative Name(s) |
|---|
| C1s esterase. |
| Reaction catalysed |
|---|
| Cleavage of Arg-|-Ala bond in complement component C4 to form C4a and C4b, and Lys(or Arg)-|-Lys bond in complement component C2 to form C2a and C2b: the 'classical' pathway C3 convertase |
| Comment(s) |
|---|
- Activated from proenzyme C1s in plasma by the activated complement
subcomponent C1r.
- Belongs to peptidase family S1.
|
| Cross-references |
|---|
| PROSITE | PDOC00124 |
| BRENDA | 3.4.21.42 |
| EC2PDB | 3.4.21.42 |
| ExplorEnz | 3.4.21.42 |
| PRIAM enzyme-specific profiles | 3.4.21.42 |
| KEGG Ligand Database for Enzyme Nomenclature | 3.4.21.42 |
| IUBMB Enzyme Nomenclature | 3.4.21.42 |
| IntEnz | 3.4.21.42 |
| MEDLINE | Find literature relating to 3.4.21.42 |
| MetaCyc | 3.4.21.42 |
| UniProtKB/Swiss-Prot |
|
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