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A new class EC 7, Translocases, has been added to the EC list. It will be part of ENZYME from release 2018_10. Read more about EC 7 here.

ENZYME entry: EC

Accepted Name
Snake venom factor V activator.
Alternative Name(s)
Factor V-activating proteinase.
RVV-V component.
Reaction catalysed
Fully activates human clotting factor V by a single cleavage at the 1545-Trp-Tyr-Leu-Arg-|-Ser-Asn-Asn-Gly-1552 bond. Cattle, but not rabbit, factor V is cleaved, and no other proteins of the clotting system are attacked. Esterase activity is observed on Bz-Arg-OEt and Tos-Arg-OMe, and amidase activity on Phe-pipecolyl-Arg-NHPhNO(2)
  • Inhibited by diisopropyl fluorophosphate.
  • Belongs to peptidase family S1.
PRIAM enzyme-specific profiles3.4.21.95
KEGG Ligand Database for Enzyme Nomenclature3.4.21.95
IUBMB Enzyme Nomenclature3.4.21.95
MEDLINEFind literature relating to
P18964, VSPA_DABSI;  Q9PT41, VSPF5_MACLB;  P18965, VSPG_DABSI;  

View entry in original ENZYME format
View entry in raw text format (no links)
All UniProtKB/Swiss-Prot entries referenced in this entry, with possibility to download in different formats, align etc.
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 3.4.21.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 3.4.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 3.-.-.-