A new class EC 7, Translocases, has been added to the EC list. It will be part of ENZYME from release 2018_10. Read more about EC 7 here.
ENZYME entry: EC 3.4.21.95
| Accepted Name |
|---|
| Snake venom factor V activator.
|
| Alternative Name(s) |
|---|
| Factor V-activating proteinase. |
| RVV-V component. |
| Reaction catalysed |
|---|
| Fully activates human clotting factor V by a single cleavage at the 1545-Trp-Tyr-Leu-Arg-|-Ser-Asn-Asn-Gly-1552 bond. Cattle, but not rabbit, factor V is cleaved, and no other proteins of the clotting system are attacked. Esterase activity is observed on Bz-Arg-OEt and Tos-Arg-OMe, and amidase activity on Phe-pipecolyl-Arg-NHPhNO(2) |
| Comment(s) |
|---|
- Inhibited by diisopropyl fluorophosphate.
- Belongs to peptidase family S1.
|
| Cross-references |
|---|
| PROSITE | PDOC00124 |
| BRENDA | 3.4.21.95 |
| EC2PDB | 3.4.21.95 |
| ExplorEnz | 3.4.21.95 |
| PRIAM enzyme-specific profiles | 3.4.21.95 |
| KEGG Ligand Database for Enzyme Nomenclature | 3.4.21.95 |
| IUBMB Enzyme Nomenclature | 3.4.21.95 |
| IntEnz | 3.4.21.95 |
| MEDLINE | Find literature relating to 3.4.21.95 |
| MetaCyc | 3.4.21.95 |
| UniProtKB/Swiss-Prot |
|
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All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 3.-.-.-