ENZYME entry: EC 3.4.24.18
Accepted Name |
meprin A.
|
Alternative Name(s) |
endopeptidase-2. |
Reaction catalysed |
Hydrolysis of protein and peptide substrates preferentially on carboxyl side of hydrophobic residues |
Comment(s) |
- A membrane-bound metalloendopeptidase of rat and mouse kidney and
intestinal brush borders, and salivary ducts.
- Differences from EC 3.4.24.11 include insensitivity to phosphoramidon
and thiorphan.
- PABA-peptide hydrolase is a very similar enzyme found in human
intestinal microvilli.
- Belongs to peptidase family M12A.
|
Cross-references |
BRENDA | 3.4.24.18 |
EC2PDB | 3.4.24.18 |
ExplorEnz | 3.4.24.18 |
PRIAM enzyme-specific profiles | 3.4.24.18 |
KEGG Ligand Database for Enzyme Nomenclature | 3.4.24.18 |
IUBMB Enzyme Nomenclature | 3.4.24.18 |
IntEnz | 3.4.24.18 |
MEDLINE | Find literature relating to 3.4.24.18 |
MetaCyc | 3.4.24.18 |
Rhea expert-curated reactions | 3.4.24.18 |
UniProtKB/Swiss-Prot |
|
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