A new class EC 7, Translocases, has been added to the EC list. It will be part of ENZYME from release 2018_10. Read more about EC 7 here.
ENZYME entry: EC 3.5.99.10
| Accepted Name |
|---|
| 2-iminobutanoate/2-iminopropanoate deaminase.
|
| Alternative Name(s) |
|---|
| Enamine/imine deaminase. |
| Reaction catalysed |
|---|
- 2-iminobutanoate + H(2)O <=> 2-oxobutanoate + NH(3)
- 2-iminopropanoate + H(2)O <=> pyruvate + NH(3)
|
| Comment(s) |
|---|
- This enzyme, which has been found in all species and tissues
examined, catalyzes the hydrolytic deamination of imine intermediates
formed by several types of pyridoxal-5'-phosphate-dependent
dehydratases, such as EC 4.3.1.19 and EC 4.3.1.17.
- The reactions, which can occur spontaneously, are accelerated to
minimize the cellular damage that could be caused by these reactive
intermediates.
|
| Cross-references |
|---|
| BRENDA | 3.5.99.10 |
| EC2PDB | 3.5.99.10 |
| ExplorEnz | 3.5.99.10 |
| PRIAM enzyme-specific profiles | 3.5.99.10 |
| KEGG Ligand Database for Enzyme Nomenclature | 3.5.99.10 |
| IUBMB Enzyme Nomenclature | 3.5.99.10 |
| IntEnz | 3.5.99.10 |
| MEDLINE | Find literature relating to 3.5.99.10 |
| MetaCyc | 3.5.99.10 |
| UniProtKB/Swiss-Prot |
| Q94JQ4, RIDA_ARATH; | P37552, RIDA_BACSU; | Q3T114, RIDA_BOVIN; |
| P80601, RIDA_CAPHI; | P0AF94, RIDA_ECOL6; | P0AF93, RIDA_ECOLI; |
| P52758, RIDA_HUMAN; | P52760, RIDA_MOUSE; | Q8U308, RIDA_PYRFU; |
| P52759, RIDA_RAT; | Q7CP78, RIDA_SALTY; | P0AF95, RIDA_SHIFL; |
|
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UniProtKB/Swiss-Prot entries corresponding to 3.5.99.-
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