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ENZYME entry: EC 3.5.99.10
Accepted Name |
2-iminobutanoate/2-iminopropanoate deaminase.
|
Alternative Name(s) |
enamine/imine deaminase. |
Reaction catalysed |
- 2-iminobutanoate + H2O <=> 2-oxobutanoate + NH4(+)
- 2-iminopropanoate + H2O <=> NH4(+) + pyruvate
|
Comment(s) |
- This enzyme, which has been found in all species and tissues
examined, catalyzes the hydrolytic deamination of imine intermediates
formed by several types of pyridoxal-5'-phosphate-dependent
dehydratases, such as EC 4.3.1.19 and EC 4.3.1.17.
- The reactions, which can occur spontaneously, are accelerated to
minimize the cellular damage that could be caused by these reactive
intermediates.
|
Cross-references |
BRENDA | 3.5.99.10 |
EC2PDB | 3.5.99.10 |
ExplorEnz | 3.5.99.10 |
PRIAM enzyme-specific profiles | 3.5.99.10 |
KEGG Ligand Database for Enzyme Nomenclature | 3.5.99.10 |
IUBMB Enzyme Nomenclature | 3.5.99.10 |
IntEnz | 3.5.99.10 |
MEDLINE | Find literature relating to 3.5.99.10 |
MetaCyc | 3.5.99.10 |
Rhea expert-curated reactions | 3.5.99.10 |
UniProtKB/Swiss-Prot |
Q94JQ4, RIDA_ARATH; | P37552, RIDA_BACSU; | Q3T114, RIDA_BOVIN; |
P80601, RIDA_CAPHI; | A0A1J1DL12, RIDA_DERFA; | P0AF94, RIDA_ECOL6; |
P0AF93, RIDA_ECOLI; | P52758, RIDA_HUMAN; | P52760, RIDA_MOUSE; |
Q8U308, RIDA_PYRFU; | P52759, RIDA_RAT; | Q7CP78, RIDA_SALTY; |
P0AF95, RIDA_SHIFL; |
|
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ENZYME /
UniProtKB/Swiss-Prot entries corresponding to 3.5.99.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 3.5.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 3.-.-.-