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ENZYME entry: EC 4.1.1.15

Accepted Name
Glutamate decarboxylase.
Alternative Name(s)
L-glutamate 1-carboxy-lyase.
Reaction catalysed
L-glutamate <=> 4-aminobutanoate + CO(2)
Cofactor(s)
Pyridoxal 5'-phosphate.
Comment(s)
The brain enzyme also acts on L-cysteate, 3-sulfino-L-alanine and L-aspartate.
Cross-references
PROSITEPDOC00329
BRENDA4.1.1.15
EC2PDB4.1.1.15
ExplorEnz4.1.1.15
PRIAM enzyme-specific profiles4.1.1.15
KEGG Ligand Database for Enzyme Nomenclature4.1.1.15
IUBMB Enzyme Nomenclature4.1.1.15
IntEnz4.1.1.15
MEDLINEFind literature relating to 4.1.1.15
MetaCyc4.1.1.15
Rhea expert-curated reactions4.1.1.15
UniProtKB/Swiss-Prot
Q42521, DCE1_ARATH;  Q0VCA1, DCE1_BOVIN;  A0PA85, DCE1_CANLF;  
P14748, DCE1_FELCA;  Q99259, DCE1_HUMAN;  P48318, DCE1_MOUSE;  
Q5IS68, DCE1_PANTR;  P48319, DCE1_PIG;  Q5R7S7, DCE1_PONAB;  
P18088, DCE1_RAT;  Q42472, DCE2_ARATH;  Q4PRC2, DCE2_CANLF;  
Q05329, DCE2_HUMAN;  P48320, DCE2_MOUSE;  P48321, DCE2_PIG;  
Q05683, DCE2_RAT;  Q9ZPS4, DCE3_ARATH;  Q9ZPS3, DCE4_ARATH;  
Q9LSH2, DCE5_ARATH;  P58228, DCEA_ECO57;  P69909, DCEA_ECOL6;  
P69908, DCEA_ECOLI;  Q9F5P3, DCEA_LISMO;  Q83PR1, DCEA_SHIFL;  
P69911, DCEB_ECO57;  Q8FHG5, DCEB_ECOL6;  P69910, DCEB_ECOLI;  
Q928R9, DCEB_LISIN;  Q9EYW9, DCEB_LISMO;  P69912, DCEB_SHIFL;  
Q928K4, DCEC_LISIN;  Q8Y4K4, DCEC_LISMO;  P20228, DCE_DROME;  
Q9CG20, DCE_LACLA;  O30418, DCE_LACLM;  Q07346, DCE_PETHY;  
P54767, DCE_SOLLC;  Q04792, DCE_YEAST;  Q5E5Y7, GADA_ALIF1;  
Q54VQ5, GADA_DICDI;  Q54IJ3, GADB_DICDI;  P16580, GLNA_CHICK;  
O58679, MFNA_PYRHO;  

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All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 4.1.1.-
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