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ENZYME

ENZYME class: 4.1.-.-


Release of 05-Feb-25

4.-.-.-: Lyases
4.1.-.-: Carbon-carbon lyases

All UniProtKB/Swiss-Prot entries corresponding to class 4.1.-.-.

The following ENZYME entries belong to class 4.1.-.-:

4.1.1.1pyruvate decarboxylase
4.1.1.2oxalate decarboxylase
4.1.1.3Transferred entry: 4.1.1.112 and 7.2.4.2
4.1.1.4acetoacetate decarboxylase
4.1.1.5acetolactate decarboxylase
4.1.1.6cis-aconitate decarboxylase
4.1.1.7benzoylformate decarboxylase
4.1.1.8oxalyl-CoA decarboxylase
4.1.1.9malonyl-CoA decarboxylase
4.1.1.10Transferred entry: 4.1.1.12
4.1.1.11aspartate 1-decarboxylase
4.1.1.12aspartate 4-decarboxylase
4.1.1.13Deleted entry
4.1.1.14valine decarboxylase
4.1.1.15glutamate decarboxylase
4.1.1.16hydroxyglutamate decarboxylase
4.1.1.17ornithine decarboxylase
4.1.1.18lysine decarboxylase
4.1.1.19arginine decarboxylase
4.1.1.20diaminopimelate decarboxylase
4.1.1.21phosphoribosylaminoimidazole carboxylase
4.1.1.22histidine decarboxylase
4.1.1.23orotidine-5'-phosphate decarboxylase
4.1.1.24aminobenzoate decarboxylase
4.1.1.25tyrosine decarboxylase
4.1.1.26Transferred entry: 4.1.1.28
4.1.1.27Transferred entry: 4.1.1.28
4.1.1.28aromatic-L-amino-acid decarboxylase
4.1.1.29sulfinoalanine decarboxylase
4.1.1.30pantothenoylcysteine decarboxylase
4.1.1.31phosphoenolpyruvate carboxylase
4.1.1.32phosphoenolpyruvate carboxykinase (GTP)
4.1.1.33diphosphomevalonate decarboxylase
4.1.1.34dehydro-L-gulonate decarboxylase
4.1.1.35UDP-glucuronate decarboxylase
4.1.1.36phosphopantothenoylcysteine decarboxylase
4.1.1.37uroporphyrinogen decarboxylase
4.1.1.38phosphoenolpyruvate carboxykinase (diphosphate)
4.1.1.39ribulose-bisphosphate carboxylase
4.1.1.40hydroxypyruvate decarboxylase
4.1.1.41Transferred entry: 7.2.4.3
4.1.1.42carnitine decarboxylase
4.1.1.43phenylpyruvate decarboxylase
4.1.1.444-carboxymuconolactone decarboxylase
4.1.1.45aminocarboxymuconate-semialdehyde decarboxylase
4.1.1.46o-pyrocatechuate decarboxylase
4.1.1.47tartronate-semialdehyde synthase
4.1.1.48indole-3-glycerol-phosphate synthase
4.1.1.49phosphoenolpyruvate carboxykinase (ATP)
4.1.1.50adenosylmethionine decarboxylase
4.1.1.513-hydroxy-2-methylpyridine-4,5-dicarboxylate 4-decarboxylase
4.1.1.526-methylsalicylate decarboxylase
4.1.1.53phenylalanine decarboxylase
4.1.1.54dihydroxyfumarate decarboxylase
4.1.1.554,5-dihydroxyphthalate decarboxylase
4.1.1.563-oxolaurate decarboxylase
4.1.1.57methionine decarboxylase
4.1.1.58orsellinate decarboxylase
4.1.1.59gallate decarboxylase
4.1.1.60stipitatonate decarboxylase
4.1.1.614-hydroxybenzoate decarboxylase
4.1.1.62gentisate decarboxylase
4.1.1.63protocatechuate decarboxylase
4.1.1.642,2-dialkylglycine decarboxylase (pyruvate)
4.1.1.65phosphatidylserine decarboxylase
4.1.1.66uracil-5-carboxylate decarboxylase
4.1.1.67UDP-galacturonate decarboxylase
4.1.1.685-oxopent-3-ene-1,2,5-tricarboxylate decarboxylase
4.1.1.693,4-dihydroxyphthalate decarboxylase
4.1.1.70Transferred entry: 7.2.4.5
4.1.1.712-oxoglutarate decarboxylase
4.1.1.72branched-chain-2-oxoacid decarboxylase
4.1.1.73tartrate decarboxylase
4.1.1.74indolepyruvate decarboxylase
4.1.1.755-guanidino-2-oxopentanoate decarboxylase
4.1.1.76arylmalonate decarboxylase
4.1.1.772-oxo-3-hexenedioate decarboxylase
4.1.1.78acetylenedicarboxylate decarboxylase
4.1.1.79sulfopyruvate decarboxylase
4.1.1.804-hydroxyphenylpyruvate decarboxylase
4.1.1.81threonine-phosphate decarboxylase
4.1.1.82phosphonopyruvate decarboxylase
4.1.1.834-hydroxyphenylacetate decarboxylase
4.1.1.84D-dopachrome decarboxylase
4.1.1.853-dehydro-L-gulonate-6-phosphate decarboxylase
4.1.1.86diaminobutyrate decarboxylase
4.1.1.87malonyl-[malonate decarboxylase] decarboxylase
4.1.1.88biotin-independent malonate decarboxylase
4.1.1.89Transferred entry: 7.2.4.4
4.1.1.90peptidyl-glutamate 4-carboxylase
4.1.1.91salicylate decarboxylase
4.1.1.92indole-3-carboxylate decarboxylase
4.1.1.93pyrrole-2-carboxylate decarboxylase
4.1.1.94ethylmalonyl-CoA decarboxylase
4.1.1.95L-glutamyl-[BtrI acyl-carrier protein] decarboxylase
4.1.1.96carboxynorspermidine decarboxylase
4.1.1.972-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase
4.1.1.984-hydroxy-3-polyprenylbenzoate decarboxylase
4.1.1.99phosphomevalonate decarboxylase
4.1.1.100prephenate decarboxylase
4.1.1.101malolactic enzyme
4.1.1.102phenacrylate decarboxylase
4.1.1.103gamma-resorcylate decarboxylase
4.1.1.1043-dehydro-4-phosphotetronate decarboxylase
4.1.1.105L-tryptophan decarboxylase
4.1.1.106fatty acid photodecarboxylase
4.1.1.1073,4-dihydroxyphenylacetaldehyde synthase
4.1.1.1084-hydroxyphenylacetaldehyde synthase
4.1.1.109phenylacetaldehyde synthase
4.1.1.110bisphosphomevalonate decarboxylase
4.1.1.111siroheme decarboxylase
4.1.1.112oxaloacetate decarboxylase
4.1.1.113trans-aconitate decarboxylase
4.1.1.114cis-3-alkyl-4-alkyloxetan-2-one decarboxylase
4.1.1.115indoleacetate decarboxylase
4.1.1.116D-ornithine/D-lysine decarboxylase
4.1.1.1172-[(L-alanin-3-ylcarbamoyl)methyl]-2-hydroxybutanedioate decarboxylase
4.1.1.118isophthalyl-CoA decarboxylase
4.1.1.119phenylacetate decarboxylase
4.1.1.1203-oxoisoapionate decarboxylase
4.1.1.1213-oxoisoapionate-4-phosphate decarboxylase
4.1.1.122L-cysteate decarboxylase
4.1.1.123phenyl-phosphate phosphatase/carboxylase
4.1.1.124malonyl-[acp] decarboxylase
4.1.1.1254-carboxy-3-alkylbut-2-enoyl-[ACP] decarboxylase
4.1.1.126anhydromevalonate phosphate decarboxylase
4.1.1.127carboxyaminopropylagmatine decarboxylase
4.1.1.128UDP-N-acetyl-alpha-D-glucosaminuronate decarboxylase
4.1.1.1291'-carboxy-chondrochloren decarboxylase
4.1.1.n1Transferred entry: 4.1.1.97
4.1.1.n2Transferred entry: 4.1.1.94
4.1.2.1Transferred entry: 4.1.3.16
4.1.2.2ketotetrose-phosphate aldolase
4.1.2.3Deleted entry
4.1.2.4deoxyribose-phosphate aldolase
4.1.2.5L-threonine aldolase
4.1.2.6Deleted entry
4.1.2.7Transferred entry: 4.1.2.13
4.1.2.8indole-3-glycerol-phosphate lyase
4.1.2.9phosphoketolase
4.1.2.10(R)-mandelonitrile lyase
4.1.2.11hydroxymandelonitrile lyase
4.1.2.122-dehydropantoate aldolase
4.1.2.13fructose-bisphosphate aldolase
4.1.2.142-dehydro-3-deoxy-phosphogluconate aldolase
4.1.2.15Transferred entry: 2.5.1.54
4.1.2.16Transferred entry: 2.5.1.55
4.1.2.17L-fuculose-phosphate aldolase
4.1.2.182-dehydro-3-deoxy-L-pentonate aldolase
4.1.2.19rhamnulose-1-phosphate aldolase
4.1.2.202-dehydro-3-deoxyglucarate aldolase
4.1.2.212-dehydro-3-deoxy-6-phosphogalactonate aldolase
4.1.2.22fructose-6-phosphate phosphoketolase
4.1.2.233-deoxy-D-manno-octulosonate aldolase
4.1.2.24dimethylaniline-N-oxide aldolase
4.1.2.25dihydroneopterin aldolase
4.1.2.26phenylserine aldolase
4.1.2.27sphinganine-1-phosphate aldolase
4.1.2.282-dehydro-3-deoxy-D-pentonate aldolase
4.1.2.295-dehydro-2-deoxyphosphogluconate aldolase
4.1.2.30Transferred entry: 1.14.14.32
4.1.2.31Transferred entry: 4.1.3.16
4.1.2.32trimethylamine-oxide aldolase
4.1.2.33fucosterol-epoxide lyase
4.1.2.344-(2-carboxyphenyl)-2-oxobut-3-enoate aldolase
4.1.2.35propioin synthase
4.1.2.36lactate aldolase
4.1.2.37Transferred entry: 4.1.2.46 and 4.1.2.47
4.1.2.38benzoin aldolase
4.1.2.39Transferred entry: 4.1.2.46 and 4.1.2.47
4.1.2.40tagatose-bisphosphate aldolase
4.1.2.41Transferred entry: 4.1.2.61
4.1.2.42D-threonine aldolase
4.1.2.433-hexulose-6-phosphate synthase
4.1.2.442,3-epoxybenzoyl-CoA dihydrolase
4.1.2.45trans-o-hydroxybenzylidenepyruvate hydratase-aldolase
4.1.2.46aliphatic (R)-hydroxynitrile lyase
4.1.2.47(S)-hydroxynitrile lyase
4.1.2.48low-specificity L-threonine aldolase
4.1.2.49L-allo-threonine aldolase
4.1.2.506-carboxytetrahydropterin synthase
4.1.2.512-dehydro-3-deoxy-D-gluconate aldolase
4.1.2.524-hydroxy-2-oxoheptanedioate aldolase
4.1.2.532-keto-3-deoxy-L-rhamnonate aldolase
4.1.2.54L-threo-3-deoxy-hexylosonate aldolase
4.1.2.552-dehydro-3-deoxy-phosphogluconate/2-dehydro-3-deoxy-6-phosphogalactonate
4.1.2.55aldolase
4.1.2.562-amino-4,5-dihydroxy-6-oxo-7-(phosphonooxy)heptanoate synthase
4.1.2.57sulfofructosephosphate aldolase
4.1.2.582-dehydro-3,6-dideoxy-6-sulfogluconate aldolase
4.1.2.59dihydroneopterin phosphate aldolase
4.1.2.60dihydroneopterin triphosphate aldolase
4.1.2.61feruloyl-CoA hydratase/lyase
4.1.2.625-deoxyribulose 1-phosphate aldolase
4.1.2.632-hydroxyacyl-CoA lyase
4.1.2.642-dehydro-3-deoxy-L-fuconate aldolase
4.1.2.65ferulate hydratase/lyase
4.1.2.664-coumarate hydratase/lyase
4.1.2.n1Transferred entry: 4.1.2.44
4.1.2.n2Transferred entry: 4.1.2.63
4.1.2.n3Transferred entry: 4.1.2.53
4.1.2.n4Transferred entry: 4.1.2.52
4.1.2.n5Transferred entry: 2.2.1.10
4.1.2.n6Transferred entry: 4.1.2.56
4.1.3.1isocitrate lyase
4.1.3.2Transferred entry: 2.3.3.9
4.1.3.3N-acetylneuraminate lyase
4.1.3.4hydroxymethylglutaryl-CoA lyase
4.1.3.5Transferred entry: 2.3.3.10
4.1.3.6citrate (pro-3S)-lyase
4.1.3.7Transferred entry: 2.3.3.1
4.1.3.8Transferred entry: 2.3.3.8
4.1.3.9Transferred entry: 2.3.3.11
4.1.3.10Transferred entry: 2.3.3.7
4.1.3.11Transferred entry: 2.3.3.12
4.1.3.12Transferred entry: 2.3.3.13
4.1.3.13oxalomalate lyase
4.1.3.14L-erythro-3-hydroxyaspartate aldolase
4.1.3.15Transferred entry: 2.2.1.5
4.1.3.164-hydroxy-2-oxoglutarate aldolase
4.1.3.174-hydroxy-4-methyl-2-oxoglutarate aldolase
4.1.3.18Transferred entry: 2.2.1.6
4.1.3.19Transferred entry: 2.5.1.56
4.1.3.20Transferred entry: 2.5.1.57
4.1.3.21Transferred entry: 2.3.3.14
4.1.3.22citramalate lyase
4.1.3.23Transferred entry: 2.3.3.2
4.1.3.24malyl-CoA lyase
4.1.3.25(S)-citramalyl-CoA lyase
4.1.3.263-hydroxy-3-isohexenylglutaryl-CoA lyase
4.1.3.27anthranilate synthase
4.1.3.28Transferred entry: 2.3.3.3
4.1.3.29Transferred entry: 2.3.3.4
4.1.3.30methylisocitrate lyase
4.1.3.31Transferred entry: 2.3.3.5
4.1.3.322,3-dimethylmalate lyase
4.1.3.33Transferred entry: 2.3.3.6
4.1.3.34citryl-CoA lyase
4.1.3.35(1-hydroxycyclohexan-1-yl)acetyl-CoA lyase
4.1.3.361,4-dihydroxy-2-naphthoyl-CoA synthase
4.1.3.37Transferred entry: 2.2.1.7
4.1.3.38aminodeoxychorismate lyase
4.1.3.394-hydroxy-2-oxovalerate aldolase
4.1.3.40chorismate lyase
4.1.3.413-hydroxy-D-aspartate aldolase
4.1.3.42(4S)-4-hydroxy-2-oxoglutarate aldolase
4.1.3.434-hydroxy-2-oxohexanoate aldolase
4.1.3.44tRNA 4-demethylwyosine synthase (AdoMet-dependent)
4.1.3.453-hydroxybenzoate synthase
4.1.3.46(R)-citramalyl-CoA lyase
4.1.3.n1Transferred entry: 4.1.3.43
4.1.99.1tryptophanase
4.1.99.2tyrosine phenol-lyase
4.1.99.3deoxyribodipyrimidine photo-lyase
4.1.99.4Transferred entry: 3.5.99.7
4.1.99.5aldehyde oxygenase (deformylating)
4.1.99.6Transferred entry: 4.2.3.6
4.1.99.7Transferred entry: 4.2.3.9
4.1.99.8Transferred entry: 4.2.3.119 and 4.2.3.120
4.1.99.9Transferred entry: 4.2.3.15
4.1.99.10Transferred entry: 4.2.3.16
4.1.99.11benzylsuccinate synthase
4.1.99.123,4-dihydroxy-2-butanone-4-phosphate synthase
4.1.99.13(6-4)DNA photolyase
4.1.99.14spore photoproduct lyase
4.1.99.15Deleted entry
4.1.99.16geosmin synthase
4.1.99.17phosphomethylpyrimidine synthase
4.1.99.18Transferred entry: 4.1.99.22 and 4.6.1.17
4.1.99.192-iminoacetate synthase
4.1.99.203-amino-4-hydroxybenzoate synthase
4.1.99.21Transferred entry: 4.2.3.153
4.1.99.22GTP 3',8-cyclase
4.1.99.235-hydroxybenzimidazole synthase
4.1.99.24L-tyrosine isonitrile synthase
4.1.99.25L-tryptophan isonitrile synthase
4.1.99.263-amino-5-[(4-hydroxyphenyl)methyl]-4,4-dimethylpyrrolidin-2-one
4.1.99.26synthase
4.1.99.27cyclopenase
4.1.99.283'-dehydrocarminate deglycosidase
4.1.99.295,8-dihydroxy-2-naphthoate synthase