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ENZYME

ENZYME entry: EC 4.1.1.23

Accepted Name
orotidine-5'-phosphate decarboxylase
Alternative Name(s)
OMPdcase
OMP decarboxylase
orotidine-5'-phosphate carboxy-lyase
orotidylic decarboxylase
UMP synthase
uridine 5'-monophosphate synthase
Reaction catalysed
H(+) + orotidine 5'-phosphate = CO2 + UMP
Comment(s)
The enzyme from higher eukaryotes is identical with EC 2.4.2.10.
Cross-references
BRENDA4.1.1.23
EC2PDB4.1.1.23
ExplorEnz4.1.1.23
PRIAM enzyme-specific profiles4.1.1.23
KEGG Ligand Database for Enzyme Nomenclature4.1.1.23
IUBMB Enzyme Nomenclature4.1.1.23
IntEnz4.1.1.23
MEDLINEFind literature relating to 4.1.1.23
MetaCyc4.1.1.23
Rhea expert-curated reactions4.1.1.23
UniProtKB/Swiss-Prot
Q8YSY4, PYRFE_NOSS1Q6F9Z3, PYRF_ACIADB7H3K6, PYRF_ACIB3
B7I534, PYRF_ACIB5B2HZE8, PYRF_ACIBCB0VN04, PYRF_ACIBS
A3M508, PYRF_ACIBTB0VD17, PYRF_ACIBYA3N0A0, PYRF_ACTP2
B3GXH2, PYRF_ACTP7B0BP16, PYRF_ACTPJA6VPK5, PYRF_ACTSZ
Q9Y9D9, PYRF_AERPEB6JCI7, PYRF_AFIC5P58638, PYRF_AGRFC
Q21RX7, PYRF_ALBFTQ0VNQ9, PYRF_ALCBSQ5E3Z6, PYRF_ALIF1
B5FG54, PYRF_ALIFMB6EIY4, PYRF_ALISLQ0AA48, PYRF_ALKEH
B9JZC0, PYRF_ALLAMB8J9L8, PYRF_ANAD2Q2IGK0, PYRF_ANADE
Q5PB36, PYRF_ANAMMB4UGH8, PYRF_ANASKO67520, PYRF_AQUAE
O29333, PYRF_ARCFUQ5P5M2, PYRF_AROAEQ5J2D0, PYRF_ASPAW
O13410, PYRF_ASPFUQ96WP7, PYRF_ASPKAP07817, PYRF_ASPNG
O13416, PYRF_ASPORQ9P8X9, PYRF_AURPUA1KBR9, PYRF_AZOSB
C3P653, PYRF_BACAAC3L743, PYRF_BACACQ81WF5, PYRF_BACAN
B7JJX0, PYRF_BACC0Q732I6, PYRF_BACC1B7IUP3, PYRF_BACC2
C1EPP7, PYRF_BACC3B7H6L9, PYRF_BACC4B7HLL7, PYRF_BACC7
P46535, PYRF_BACCLA7GRK8, PYRF_BACCNB9IVW0, PYRF_BACCQ
Q819S6, PYRF_BACCRQ636E3, PYRF_BACCZQ5LH12, PYRF_BACFN
Q64XW6, PYRF_BACFRQ6HET1, PYRF_BACHKQ65JU4, PYRF_BACLD
A9VTC3, PYRF_BACMKA8FD20, PYRF_BACP2P25971, PYRF_BACSU
Q8A012, PYRF_BACTNQ44843, PYRF_BARBAQ1LTG7, PYRF_BAUCH
Q2KY06, PYRF_BORA1Q7WNS8, PYRF_BORBRQ7W138, PYRF_BORPA
A9I6E7, PYRF_BORPDQ7VTM9, PYRF_BORPEQ9LCT0, PYRF_BRADU
A5E8J8, PYRF_BRASBA4YJQ1, PYRF_BRASOB2S9C4, PYRF_BRUA1
Q2YQU9, PYRF_BRUA2Q57AD4, PYRF_BRUABA9M9W1, PYRF_BRUC2
C0RG13, PYRF_BRUMBQ8YE79, PYRF_BRUMEB0CJX7, PYRF_BRUSI
Q8FXW9, PYRF_BRUSUB8D963, PYRF_BUCA5P57358, PYRF_BUCAI
Q8K9Q1, PYRF_BUCAPB8D7G7, PYRF_BUCATQ89AL6, PYRF_BUCBP
B9MS23, PYRF_CALBDP58883, PYRF_CALS4A4XKT3, PYRF_CALS8
A8Z6D0, PYRF_CAMC1A7GWZ8, PYRF_CAMC5A0RQJ5, PYRF_CAMFF
A7HZG2, PYRF_CAMHCA8FKG8, PYRF_CAMJ8A7H4Z6, PYRF_CAMJD
Q9PIC1, PYRF_CAMJEA1VYA1, PYRF_CAMJJQ5HW86, PYRF_CAMJR
B9KFP1, PYRF_CAMLRP13649, PYRF_CANALQ01378, PYRF_CANBO
Q9C150, PYRF_CANDCP33283, PYRF_CANGAP32430, PYRF_CANMA
Q12595, PYRF_CANPAO42771, PYRF_CANTRQ3AC06, PYRF_CARHZ
B0T410, PYRF_CAUSKQ9ABW5, PYRF_CAUVCB8GXJ5, PYRF_CAUVN
B3PDW7, PYRF_CELJUQ3IY00, PYRF_CERS4A0LYL6, PYRF_CHRFK
Q1QVK2, PYRF_CHRSDQ7NTL2, PYRF_CHRVOB5EIT8, PYRF_CITBB
Q97FS5, PYRF_CLOABA7FYI9, PYRF_CLOB1C3KU84, PYRF_CLOB6
A5I6W8, PYRF_CLOBHC1FLB3, PYRF_CLOBJB1INE4, PYRF_CLOBK
A7GIH9, PYRF_CLOBLB1L1E4, PYRF_CLOBMA5N2L5, PYRF_CLOK5
A0Q2N3, PYRF_CLONNQ0TRB0, PYRF_CLOP1Q8XL62, PYRF_CLOPE
Q0STN6, PYRF_CLOPSQ891J1, PYRF_CLOTEQ1E9A1, PYRF_COCIM
Q4VWW3, PYRF_COCPSQ482F9, PYRF_COLP3Q8FT43, PYRF_COREF
A4QEI3, PYRF_CORGBQ8NQ40, PYRF_CORGLB6J887, PYRF_COXB1
B6J1D4, PYRF_COXB2A9KCT0, PYRF_COXBNA9NC23, PYRF_COXBR
Q83E06, PYRF_COXBUQ1LIV4, PYRF_CUPMCQ0K6Y9, PYRF_CUPNH
B3R6U7, PYRF_CUPTRQ6A911, PYRF_CUTAKP79075, PYRF_CYBFA
O94127, PYRF_CYBJAQ6BY69, PYRF_DEBHAQ47AF2, PYRF_DECAR
Q3ZAI1, PYRF_DEHM1A5FP84, PYRF_DEHMBQ3ZWB0, PYRF_DEHMC
Q9RSC5, PYRF_DEIRAA9BS60, PYRF_DELASA8ZWP0, PYRF_DESOH
A5EVH6, PYRF_DICNVB5YFH2, PYRF_DICT6B8E2K1, PYRF_DICTD
Q9HFN9, PYRF_DIURUA7ZLA2, PYRF_ECO24B7UR89, PYRF_ECO27
B7MLV7, PYRF_ECO45B7L4B7, PYRF_ECO55P58640, PYRF_ECO57
B7NVQ5, PYRF_ECO7IB7MUC3, PYRF_ECO81B7LY40, PYRF_ECO8A
C4ZTX6, PYRF_ECOBWB1XBN2, PYRF_ECODHA7ZZM0, PYRF_ECOHS
Q0TI84, PYRF_ECOL5Q8FHU2, PYRF_ECOL6B1ITH3, PYRF_ECOLC
P08244, PYRF_ECOLIB7N497, PYRF_ECOLUB6I9Z7, PYRF_ECOSE
B1LH07, PYRF_ECOSMQ1RC84, PYRF_ECOUTQ3YSH4, PYRF_EHRCJ
Q2GG43, PYRF_EHRCRP10652, PYRF_EMENIA4WAY2, PYRF_ENT38
Q834E3, PYRF_ENTFAQ757S1, PYRF_EREGSQ2N9N4, PYRF_ERYLH
B7LRZ7, PYRF_ESCF3B0S1A1, PYRF_FINM2A5FHG4, PYRF_FLAJ1
Q2J838, PYRF_FRACCQ8RG83, PYRF_FUSNNB9LZK2, PYRF_GEODF
Q5L0U0, PYRF_GEOKAQ39VY5, PYRF_GEOMGQ74D58, PYRF_GEOSL
C6E497, PYRF_GEOSMC5D8Q3, PYRF_GEOSWA4IM36, PYRF_GEOTN
A5G5A2, PYRF_GEOURB8F472, PYRF_GLAP5B7KL53, PYRF_GLOC7
Q7NK22, PYRF_GLOVIQ5FNS8, PYRF_GLUOXQ7VLR5, PYRF_HAEDU
Q4QJV1, PYRF_HAEI8A5UBN7, PYRF_HAEIEP43812, PYRF_HAEIN
Q2SCG0, PYRF_HAHCHQ9K9W2, PYRF_HALH5A1WUI3, PYRF_HALHL
B9LP84, PYRF_HALLTQ5V216, PYRF_HALMAB0R642, PYRF_HALS3
Q9P9M3, PYRF_HALSAP14017, PYRF_HAPCHB0TDZ7, PYRF_HELMI
B6JPA4, PYRF_HELP2Q9ZN53, PYRF_HELPJB2UW09, PYRF_HELPS
P56155, PYRF_HELPYA9B3C5, PYRF_HERA2A4G2V0, PYRF_HERAR
Q31GC7, PYRF_HYDCUQ12709, PYRF_HYPATP21594, PYRF_HYPJE
Q5QZ42, PYRF_IDILOA6SVJ9, PYRF_JANMAQ28K56, PYRF_JANSC
Q9Y726, PYRF_KAZEXB5XS09, PYRF_KLEP3P07922, PYRF_KLULA
P41769, PYRF_KLUMAP48844, PYRF_KODOHQ5FJB3, PYRF_LACAC
Q1G991, PYRF_LACDAQ049E0, PYRF_LACDBQ043A6, PYRF_LACGA
Q74J28, PYRF_LACJOQ9CFW9, PYRF_LACLAP50924, PYRF_LACLM
Q02YJ4, PYRF_LACLSP77888, PYRF_LACPLC1D549, PYRF_LARHH
Q38X21, PYRF_LATSSQ1MRK9, PYRF_LAWIPQ5X5E0, PYRF_LEGPA
A5IBR7, PYRF_LEGPCQ5ZVL5, PYRF_LEGPHQ5WWS3, PYRF_LEGPL
Q04NB4, PYRF_LEPBJQ04WJ4, PYRF_LEPBLB1XXP1, PYRF_LEPCP
Q8EXA4, PYRF_LEPINQ1WTX2, PYRF_LIGS1Q92AH6, PYRF_LISIN
C1KWD1, PYRF_LISMCQ71YI4, PYRF_LISMFB8DDS0, PYRF_LISMH
P58641, PYRF_LISMOA0AJT7, PYRF_LISW6B1HQC3, PYRF_LYSSC
Q12604, PYRF_MAGMUQ8EUY3, PYRF_MALP2Q65SI1, PYRF_MANSM
A6W097, PYRF_MARMSA1TZF4, PYRF_MARN8C6BZZ8, PYRF_MARSD
Q8TS37, PYRF_METACQ46GE2, PYRF_METBFQ12X87, PYRF_METBU
B7KUF7, PYRF_METC4Q609Y2, PYRF_METCAA9W2W3, PYRF_METEP
B3DVI6, PYRF_METI4Q57700, PYRF_METJAA9A6C3, PYRF_METM6
Q8PV88, PYRF_METMAQ6LZM2, PYRF_METMPB8IFW8, PYRF_METNO
B1ZFB1, PYRF_METPBA2SLY9, PYRF_METPPB1M7M3, PYRF_METRJ
B0UL68, PYRF_METS4Q2NHA5, PYRF_METSTQ977X5, PYRF_METTE
O26232, PYRF_METTHQ2RK39, PYRF_MOOTAP32431, PYRF_MUCCL
A0QI32, PYRF_MYCA1P0A5M7, PYRF_MYCBOA1KIH4, PYRF_MYCBP
C1AN30, PYRF_MYCBTB8ZUL5, PYRF_MYCLBQ9CCR1, PYRF_MYCLE
B2HP45, PYRF_MYCMMQ741H0, PYRF_MYCPAO08323, PYRF_MYCS2
A5U287, PYRF_MYCTAP9WIU2, PYRF_MYCTOP9WIU3, PYRF_MYCTU
A0PPJ3, PYRF_MYCUAA1T8H2, PYRF_MYCVPP24220, PYRF_MYXXD
Q3ISC9, PYRF_NATPDB9L788, PYRF_NAUPAQ5F9J2, PYRF_NEIG1
B4RKA3, PYRF_NEIG2A9M3Q3, PYRF_NEIM0Q9JV18, PYRF_NEIMA
Q9K005, PYRF_NEIMBA1KT74, PYRF_NEIMFP05035, PYRF_NEUCR
Q0AIZ1, PYRF_NITECQ82TD8, PYRF_NITEUQ1QMP2, PYRF_NITHX
Q2Y7B1, PYRF_NITMUQ3J8N5, PYRF_NITOCA6Q2C1, PYRF_NITSB
Q72DM8, PYRF_NITV2A1VF83, PYRF_NITV4B8DKC9, PYRF_NITV9
Q3SRG9, PYRF_NITWNA1SJF3, PYRF_NOCSJP58639, PYRF_NOSS1
Q2G8S2, PYRF_NOVADQ8ER36, PYRF_OCEIHQ04H28, PYRF_OENOB
Q30XT2, PYRF_OLEA2B1ZSC4, PYRF_OPITPO93864, PYRF_PACTA
Q9C131, PYRF_PARBRA1TW93, PYRF_PARC0A6LDS0, PYRF_PARD8
Q2W019, PYRF_PARM1Q7U8P3, PYRF_PARMWQ9HFV8, PYRF_PASFU
Q9CMM1, PYRF_PASMUQ6D5T3, PYRF_PECASC6DK13, PYRF_PECCP
A1APM0, PYRF_PELPDQ7Z8L4, PYRF_PENCAP09463, PYRF_PENCH
Q8J269, PYRF_PENNAA9BJH6, PYRF_PETMOQ7N4C1, PYRF_PHOLL
Q6LPE7, PYRF_PHOPRA6KWL1, PYRF_PHOV8P21593, PYRF_PHYB8
Q06375, PYRF_PICANQ6IUR4, PYRF_PICKUQ9C1J2, PYRF_PICPA
P49434, PYRF_PICSTA1VU11, PYRF_POLNAB2RME4, PYRF_PORG3
Q7MXT6, PYRF_PORGIA3PEG2, PYRF_PROM0A2C4A1, PYRF_PROM1
A8G6D9, PYRF_PROM2A9BBV1, PYRF_PROM4A2BY35, PYRF_PROM5
Q319F9, PYRF_PROM9Q7VAP8, PYRF_PROMAB4EW04, PYRF_PROMH
Q7V5Y2, PYRF_PROMMQ7V0D8, PYRF_PROMPA2BSQ0, PYRF_PROMS
Q46JD8, PYRF_PROMTQ48KP5, PYRF_PSE14Q15T09, PYRF_PSEA6
A6V3L5, PYRF_PSEA7B7V800, PYRF_PSEA8Q02P38, PYRF_PSEAB
Q59654, PYRF_PSEAEQ1ID82, PYRF_PSEE4Q4KFV3, PYRF_PSEF5
C3K758, PYRF_PSEFSA5W7B0, PYRF_PSEP1Q3K8H1, PYRF_PSEPF
B0KUJ6, PYRF_PSEPGQ88LW2, PYRF_PSEPKB1J5Q0, PYRF_PSEPW
Q884R0, PYRF_PSESMQ3IGA7, PYRF_PSET1Q4ZVD9, PYRF_PSEU2
Q4FRL9, PYRF_PSYA2Q1QA56, PYRF_PSYCKA1SYZ6, PYRF_PSYIN
Q9UZ35, PYRF_PYRABQ8U1U1, PYRF_PYRFUO58462, PYRF_PYRHO
P58642, PYRF_RALN1B2UCD6, PYRF_RALPJB3PYJ5, PYRF_RHIE6
Q2KDF0, PYRF_RHIECQ9EYV3, PYRF_RHIFHQ1MMI1, PYRF_RHIJ3
Q98DD5, PYRF_RHILOB5ZYG6, PYRF_RHILWQ92SN8, PYRF_RHIME
P43230, PYRF_RHINIQ71HN5, PYRF_RHIORQ9Y720, PYRF_RHIPU
B9J7M8, PYRF_RHIR8Q7UIA4, PYRF_RHOBAQ2J316, PYRF_RHOP2
Q07UT0, PYRF_RHOP5Q6NCY0, PYRF_RHOPAQ21CH8, PYRF_RHOPB
Q13E64, PYRF_RHOPSB3Q976, PYRF_RHOPTQ2RNS7, PYRF_RHORT
A7NS27, PYRF_ROSCSA5UPS3, PYRF_ROSS1Q5LND3, PYRF_RUEPO
Q21IS8, PYRF_SACD2Q9UVZ5, PYRF_SACFIQ9UX10, PYRF_SACS2
B5F565, PYRF_SALA4A8LY20, PYRF_SALAIQ57NV3, PYRF_SALCH
B5R486, PYRF_SALEPB5R6P3, PYRF_SALG2B4T6V0, PYRF_SALNS
Q5PD06, PYRF_SALPAB5BID8, PYRF_SALPKP58643, PYRF_SALTI
A4X621, PYRF_SALTOP07691, PYRF_SALTYP14964, PYRF_SCHCO
P14965, PYRF_SCHPOQ8EEI4, PYRF_SHEONA8FVN0, PYRF_SHESH
B2U0H4, PYRF_SHIB3Q31ZX5, PYRF_SHIBSQ32GQ2, PYRF_SHIDS
Q0T5B6, PYRF_SHIF8Q83RM1, PYRF_SHIFLQ3Z131, PYRF_SHISS
Q5WFJ5, PYRF_SHOC1A6UFC6, PYRF_SINMWQ2NT36, PYRF_SODGM
Q9HF68, PYRF_SOLCCP78748, PYRF_SORMKQ1GU89, PYRF_SPHAL
A7X1F5, PYRF_STAA1Q2FHN4, PYRF_STAA3Q2FZ71, PYRF_STAA8
Q2YXG4, PYRF_STAABQ5HGM8, PYRF_STAACA6QGA5, PYRF_STAAE
P65595, PYRF_STAAMP99145, PYRF_STAANQ6GHN1, PYRF_STAAR
Q6GA09, PYRF_STAASP65596, PYRF_STAAWQ5HPY7, PYRF_STAEQ
Q8CPJ3, PYRF_STAESQ4L5Q6, PYRF_STAHJQ49WY5, PYRF_STAS1
Q3K145, PYRF_STRA1Q8E5F0, PYRF_STRA3Q8DZQ2, PYRF_STRA5
Q9KXR8, PYRF_STRCOC0M7X0, PYRF_STRE4B4U3E1, PYRF_STREM
A8AXM8, PYRF_STRGCB4SRN9, PYRF_STRM5B2FU58, PYRF_STRMK
Q8DTV1, PYRF_STRMUQ9A077, PYRF_STRP1Q04LJ3, PYRF_STRP2
P0DC80, PYRF_STRP3B5E301, PYRF_STRP4Q5XCK8, PYRF_STRP6
C1C651, PYRF_STRP7Q8P1C0, PYRF_STRP8Q1JC81, PYRF_STRPB
Q1JM65, PYRF_STRPCQ1JHB0, PYRF_STRPDQ1J729, PYRF_STRPF
A2RF05, PYRF_STRPGB1IAM6, PYRF_STRPIB8ZMZ9, PYRF_STRPJ
Q48U10, PYRF_STRPMP0CB75, PYRF_STRPNP0DC81, PYRF_STRPQ
B2IN86, PYRF_STRPSB5XL15, PYRF_STRPZQ8DQL6, PYRF_STRR6
A4W1D9, PYRF_STRS2C0ME50, PYRF_STRS7A3CN89, PYRF_STRSV
A4VV36, PYRF_STRSYQ5LZW9, PYRF_STRT1Q5M4I0, PYRF_STRT2
Q03KS6, PYRF_STRTDB9DUH9, PYRF_STRU0C1CD54, PYRF_STRZJ
C1CJF5, PYRF_STRZPC1CQG7, PYRF_STRZTQ30QK7, PYRF_SULDN
A6Q826, PYRF_SULNBB2V790, PYRF_SULSYQ970X0, PYRF_SULTO
Q2LQ82, PYRF_SYNASQ3A6R4, PYRF_SYNC1Q31K20, PYRF_SYNE7
Q2JTW6, PYRF_SYNJAQ2JPF1, PYRF_SYNJBQ5N1T9, PYRF_SYNP6
A5GN53, PYRF_SYNPWQ0I824, PYRF_SYNS3Q3AZD9, PYRF_SYNS9
Q3AHU2, PYRF_SYNSCQ0AXG7, PYRF_SYNWWP73761, PYRF_SYNY3
C5BSJ7, PYRF_TERTTO74110, PYRF_THEACQ47R19, PYRF_THEFY
Q5JDB0, PYRF_THEKOQ9WYG7, PYRF_THEMAB0KA34, PYRF_THEP3
B0K2E7, PYRF_THEPXB9L1A9, PYRF_THERPP96076, PYRF_THET2
Q8DLT3, PYRF_THEVBQ97CS3, PYRF_THEVOQ3SK77, PYRF_THIDA
C4LEZ7, PYRF_TOLATQ8J0E6, PYRF_TORDEQ119B9, PYRF_TRIEI
B3E1T2, PYRF_TRIL1Q3MEN8, PYRF_TRIV2P15188, PYRF_USTMA
C5CQB2, PYRF_VARPSA1WGU4, PYRF_VEREIB7VH29, PYRF_VIBA3
A7MUN7, PYRF_VIBC1A5F6Y1, PYRF_VIBC3Q9KQT7, PYRF_VIBCH
C3LNL5, PYRF_VIBCMQ87N49, PYRF_VIBPAQ8D8J6, PYRF_VIBVU
Q7MLX2, PYRF_VIBVYP78724, PYRF_WICANQ8D2J1, PYRF_WIGBR
B3CN77, PYRF_WOLPPQ7MAE8, PYRF_WOLSUQ5GRJ9, PYRF_WOLTR
Q8PER4, PYRF_XANACQ4UNV9, PYRF_XANC8B0RZ30, PYRF_XANCB
Q8P3D7, PYRF_XANCPQ3BMA4, PYRF_XANE5Q2P8Z6, PYRF_XANOM
B2SHJ1, PYRF_XANOPQ5H6B9, PYRF_XANORB2I656, PYRF_XYLF2
Q9PHB0, PYRF_XYLFAB0U1D6, PYRF_XYLFMQ87FA3, PYRF_XYLFT
Q12724, PYRF_YARLIP03962, PYRF_YEASTA1JM26, PYRF_YERE8
A7FI10, PYRF_YERP3Q1C7L9, PYRF_YERPAB2K4I4, PYRF_YERPB
P58644, PYRF_YERPEA9R8T1, PYRF_YERPGQ1CJ05, PYRF_YERPN
A4TJ45, PYRF_YERPPQ66AI1, PYRF_YERPSB1JKQ0, PYRF_YERPY
Q9HFX0, PYRF_ZYGBAQ9LDN2, UMPS1_ORYSJQ8RZA1, UMPS2_ORYSJ
Q42586, UMPS_ARATHP31754, UMPS_BOVING5EDZ2, UMPS_CAEEL
P09556, UMPS_DICDIQ01637, UMPS_DROMEP11172, UMPS_HUMAN
P13439, UMPS_MOUSEQ25566, UMPS_NAEGRQ5R514, UMPS_PONAB
Q42942, UMPS_TOBAC

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