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ENZYME

ENZYME entry: EC 4.1.1.28

PURL: https://purl.expasy.org/enzyme/EC/4.1.1.28
Accepted Name
aromatic-L-amino-acid decarboxylase
Alternative Name(s)
5-hydroxytryptophan decarboxylase
aromatic amino acid decarboxylase
DOPA decarboxylase
hydroxytryptophan decarboxylase
L-DOPA decarboxylase
tryptophan decarboxylase
Reaction catalysed
  • L-dopa + H(+) = dopamine + CO2
  • 5-hydroxy-L-tryptophan + H(+) = serotonin + CO2
Comment(s)
  • Also acts on other aromatic L-amino acids, including L-tryptophan.
  • Formerly EC 4.1.1.26 and EC 4.1.1.27.
Cross-references
BRENDA4.1.1.28
EC2PDB4.1.1.28
ExplorEnz4.1.1.28
KEGG Ligand Database for Enzyme Nomenclature4.1.1.28
IUBMB Enzyme Nomenclature4.1.1.28
MEDLINEFind literature relating to 4.1.1.28
MetaCyc4.1.1.28
Rhea expert-curated reactions4.1.1.28
UniProtKB/Swiss-Prot
I0DFJ0, AADC_BACATP27718, DDC_BOVINP34751, DDC_CAEEL
P22781, DDC_CAVPOO96571, DDC_DROLEP05031, DDC_DROME
O96567, DDC_DROSIP20711, DDC_HUMANP48861, DDC_MANSE
O88533, DDC_MOUSEP80041, DDC_PIGP14173, DDC_RAT
Q6ZJK7, TDC1_ORYSJP17770, TDC_CATROP54768, TYDC1_PAPSO
A0AA51Z3J4, TYDC2_LOPWIP54769, TYDC2_PAPSOP54770, TYDC3_PAPSO
P54771, TYDC5_PAPSO

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All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 4.1.1.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 4.1.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 4.-.-.-