ENZYME entry: EC 4.1.1.28
Accepted Name |
aromatic-L-amino-acid decarboxylase.
|
Alternative Name(s) |
5-hydroxytryptophan decarboxylase. |
aromatic amino acid decarboxylase. |
DOPA decarboxylase. |
hydroxytryptophan decarboxylase. |
L-DOPA decarboxylase. |
tryptophan decarboxylase. |
Reaction catalysed |
- H(+) + L-dopa <=> CO2 + dopamine
- 5-hydroxy-L-tryptophan + H(+) <=> CO2 + serotonin
|
Comment(s) |
- Also acts on other aromatic L-amino acids, including L-tryptophan.
- Formerly EC 4.1.1.26 and EC 4.1.1.27.
|
Cross-references |
BRENDA | 4.1.1.28 |
EC2PDB | 4.1.1.28 |
ExplorEnz | 4.1.1.28 |
PRIAM enzyme-specific profiles | 4.1.1.28 |
KEGG Ligand Database for Enzyme Nomenclature | 4.1.1.28 |
IUBMB Enzyme Nomenclature | 4.1.1.28 |
IntEnz | 4.1.1.28 |
MEDLINE | Find literature relating to 4.1.1.28 |
MetaCyc | 4.1.1.28 |
Rhea expert-curated reactions | 4.1.1.28 |
UniProtKB/Swiss-Prot |
P27718, DDC_BOVIN; | P34751, DDC_CAEEL; | P22781, DDC_CAVPO; |
O96571, DDC_DROLE; | P05031, DDC_DROME; | O96567, DDC_DROSI; |
P20711, DDC_HUMAN; | P48861, DDC_MANSE; | O88533, DDC_MOUSE; |
P80041, DDC_PIG; | P14173, DDC_RAT; | Q6ZJK7, TDC1_ORYSJ; |
P17770, TDC_CATRO; | P54768, TYDC1_PAPSO; | P54769, TYDC2_PAPSO; |
P54770, TYDC3_PAPSO; | P54771, TYDC5_PAPSO; |
|
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