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ENZYME

ENZYME entry: EC 4.1.1.31

Accepted Name
phosphoenolpyruvate carboxylase
Alternative Name(s)
PEP carboxylase
PEPCase
phosphoenolpyruvic carboxylase
Reaction catalysed
oxaloacetate + phosphate <=> hydrogencarbonate + phosphoenolpyruvate
Comment(s)
  • This enzyme replenishes oxaloacetate in the tricarboxylic acid cycle when operating in the reverse direction.
  • The reaction proceeds in two steps: formation of carboxyphosphate and the enolate form of pyruvate, followed by carboxylation of the enolate and release of phosphate.
Cross-references
BRENDA4.1.1.31
EC2PDB4.1.1.31
ExplorEnz4.1.1.31
PRIAM enzyme-specific profiles4.1.1.31
KEGG Ligand Database for Enzyme Nomenclature4.1.1.31
IUBMB Enzyme Nomenclature4.1.1.31
IntEnz4.1.1.31
MEDLINEFind literature relating to 4.1.1.31
MetaCyc4.1.1.31
Rhea expert-curated reactions4.1.1.31
UniProtKB/Swiss-Prot
Q9MAH0, CAPP1_ARATHP81831, CAPP1_CHLREQ01647, CAPP1_FLAPR
P04711, CAPP1_MAIZEP10490, CAPP1_MESCRP29193, CAPP1_SACHY
P29195, CAPP1_SORBIQ02909, CAPP1_SOYBNQ5GM68, CAPP2_ARATH
Q6R2V6, CAPP2_CHLREP51059, CAPP2_MAIZEP16097, CAPP2_MESCR
P29194, CAPP2_SORBIP51061, CAPP2_SOYBNQ84VW9, CAPP3_ARATH
P15804, CAPP3_SORBIQ8GVE8, CAPP4_ARATHO28786, CAPPA_ARCFU
A8MBK0, CAPPA_CALMQQ0TRE4, CAPPA_CLOP1Q8XLE8, CAPPA_CLOPE
Q0STS8, CAPPA_CLOPSP30694, CAPPA_FLATRB0R7F9, CAPPA_HALS3
Q9HN43, CAPPA_HALSAQ03VI7, CAPPA_LEUMMQ8TMG9, CAPPA_METAC
Q469A3, CAPPA_METBFQ2FLH1, CAPPA_METHJQ8TYV1, CAPPA_METKA
Q8PS70, CAPPA_METMAA4YES9, CAPPA_METS5O27026, CAPPA_METTH
Q04D35, CAPPA_OENOBQ6L0F3, CAPPA_PICTOQ9V2Q9, CAPPA_PYRAB
Q8ZT64, CAPPA_PYRAEA4WJM7, CAPPA_PYRARA3MVZ5, CAPPA_PYRCJ
Q8TZL5, CAPPA_PYRFUO57764, CAPPA_PYRHOA1RR50, CAPPA_PYRIL
Q97WG4, CAPPA_SACS2Q4JCJ1, CAPPA_SULACC3N0D7, CAPPA_SULIA
C4KJI5, CAPPA_SULIKC3MJE5, CAPPA_SULILC3MTS7, CAPPA_SULIM
C3NJA0, CAPPA_SULINC3N8C3, CAPPA_SULIYQ96YS2, CAPPA_SULTO
A1RZN3, CAPPA_THEPDQ9FV66, CAPPB_FLATRQ9FV65, CAPPC_FLATR
Q6F6Q6, CAPP_ACIADA3MA94, CAPP_ACIBTA3MZ57, CAPP_ACTP2
A0KFU8, CAPP_AERHHA4SIM0, CAPP_AERS4Q0VRS0, CAPP_ALCBS
Q5E2E3, CAPP_ALIF1B5FBP8, CAPP_ALIFMB6EMN4, CAPP_ALISL
Q43299, CAPP_AMAHPQ5P7H5, CAPP_AROAEA8I060, CAPP_AZOC5
A1K454, CAPP_AZOSBQ7WQB3, CAPP_BORBRQ7WCA9, CAPP_BORPA
Q7W0D0, CAPP_BORPEQ89R17, CAPP_BRADUA3MLK7, CAPP_BURM7
A2SAH4, CAPP_BURM9Q62LC1, CAPP_BURMAA1V5U2, CAPP_BURMS
A3N6Z8, CAPP_BURP6Q63W75, CAPP_BURPSA4JGV5, CAPP_BURVG
Q9A871, CAPP_CAUVCQ1QX15, CAPP_CHRSDQ7P206, CAPP_CHRVO
A8AKW6, CAPP_CITK8Q93MH3, CAPP_CORCTP61448, CAPP_CORDI
Q8RQL3, CAPP_COREFP12880, CAPP_CORGLA7ZUH4, CAPP_ECO24
B7UNT2, CAPP_ECO27B7MI92, CAPP_ECO45B7LA56, CAPP_ECO55
Q8X743, CAPP_ECO57B5Z058, CAPP_ECO5EB7NU44, CAPP_ECO7I
B7MR83, CAPP_ECO81B7M710, CAPP_ECO8AC5A0C2, CAPP_ECOBW
B1XBC1, CAPP_ECODHA8A764, CAPP_ECOHSA1AID4, CAPP_ECOK1
Q0TAA4, CAPP_ECOL5Q8FB98, CAPP_ECOL6B1IVC2, CAPP_ECOLC
P00864, CAPP_ECOLIB7NFQ6, CAPP_ECOLUB6I5H2, CAPP_ECOSE
B1LNR6, CAPP_ECOSMQ1R3V5, CAPP_ECOUTC5BC63, CAPP_EDWI9
A4WG55, CAPP_ENT38B2VGA2, CAPP_ERWT9B7LUN9, CAPP_ESCF3
Q7NNJ7, CAPP_GLOVIQ4QL71, CAPP_HAEI8A5UCN0, CAPP_HAEIE
A5UIY9, CAPP_HAEIGP43920, CAPP_HAEINQ0I371, CAPP_HAES1
Q2SL23, CAPP_HAHCHB0UUJ3, CAPP_HISS2B5XZ20, CAPP_KLEP3
Q5FK38, CAPP_LACACQ1GBD4, CAPP_LACDAA8YVD9, CAPP_LACH4
A6VUQ5, CAPP_MARMSA1U2U4, CAPP_MARN8Q02735, CAPP_MEDSA
Q49136, CAPP_METEAA0QHY0, CAPP_MYCA1P46710, CAPP_MYCLE
P61449, CAPP_MYCPAA0QWX4, CAPP_MYCS2A0PPN8, CAPP_MYCUA
Q5F5A9, CAPP_NEIG1Q9JWH1, CAPP_NEIMAQ9JXG5, CAPP_NEIMB
A1KWE0, CAPP_NEIMFQ0AH90, CAPP_NITECQ82WS3, CAPP_NITEU
Q5YYG7, CAPP_NOCFAP28594, CAPP_NOSS1A1R2V3, CAPP_PAEAT
Q7U4M0, CAPP_PARMWQ143B6, CAPP_PARXLQ9CN89, CAPP_PASMU
P51062, CAPP_PEAQ6DAR6, CAPP_PECASC6DI86, CAPP_PECCP
Q9AU12, CAPP_PHAVUQ7MAX5, CAPP_PHOLLQ6LVH1, CAPP_PHOPR
P51063, CAPP_PICABA3PF64, CAPP_PROM0A8G779, CAPP_PROM2
A2BYV8, CAPP_PROM5Q318G7, CAPP_PROM9Q7V9U4, CAPP_PROMA
B4F183, CAPP_PROMHQ7V561, CAPP_PROMMQ7UZT0, CAPP_PROMP
A2BTF4, CAPP_PROMSQ48F34, CAPP_PSE14A6V1A0, CAPP_PSEA7
Q9HXV3, CAPP_PSEAEQ1IDV2, CAPP_PSEE4Q4KHK5, CAPP_PSEF5
A4XXP6, CAPP_PSEMYA5W881, CAPP_PSEP1Q3KHE4, CAPP_PSEPF
B0KS63, CAPP_PSEPGQ88MR4, CAPP_PSEPKQ886R9, CAPP_PSESM
Q3IBX6, CAPP_PSET1Q4ZWV3, CAPP_PSEU2A1SRH8, CAPP_PSYIN
Q8XWW2, CAPP_RALSOQ59757, CAPP_RHOMRQ2IU23, CAPP_RHOP2
Q07QP5, CAPP_RHOP5O32483, CAPP_RHOPAQ218E3, CAPP_RHOPB
Q139X8, CAPP_RHOPSA7NLR3, CAPP_ROSCSA9MI14, CAPP_SALAR
Q57H97, CAPP_SALCHB5FPX1, CAPP_SALDCB5QXQ1, CAPP_SALEP
B5RF49, CAPP_SALG2B4TCQ2, CAPP_SALHSB4T0W7, CAPP_SALNS
Q5PK55, CAPP_SALPAA9N0G6, CAPP_SALPBC0Q472, CAPP_SALPC
B5BJN0, CAPP_SALPKB4TQH2, CAPP_SALSVQ8Z307, CAPP_SALTI
Q8ZKM0, CAPP_SALTYA8GL86, CAPP_SERP5B0TL90, CAPP_SHEHH
A3Q9C4, CAPP_SHELPQ8EK30, CAPP_SHEONA8GZ16, CAPP_SHEPA
A8G1A9, CAPP_SHESHB2TWF1, CAPP_SHIB3Q31U32, CAPP_SHIBS
Q32AB9, CAPP_SHIDSQ0SY38, CAPP_SHIF8Q83IS7, CAPP_SHIFL
Q3YV20, CAPP_SHISSP29196, CAPP_SOLTUQ3K1U6, CAPP_STRA1
Q8E647, CAPP_STRA3Q8E0H2, CAPP_STRA5Q82HE3, CAPP_STRAW
Q9RNU9, CAPP_STRCOA8AW99, CAPP_STRGCQ8DV10, CAPP_STRMU
Q9A0U7, CAPP_STRP1Q04KL8, CAPP_STRP2P0DC98, CAPP_STRP3
Q5XD52, CAPP_STRP6Q8P1W7, CAPP_STRP8A2RFQ7, CAPP_STRPG
Q97QX6, CAPP_STRPNP0DC99, CAPP_STRPQQ8DPW5, CAPP_STRR6
A4VZZ0, CAPP_STRS2A3CP10, CAPP_STRSVA4VTQ4, CAPP_STRSY
Q5M0E6, CAPP_STRT1Q5M4Z3, CAPP_STRT2Q03LA9, CAPP_STRTD
A4VN44, CAPP_STUS1P06516, CAPP_SYNP6A5GIW5, CAPP_SYNPW
P74299, CAPP_SYNY3P51060, CAPP_THES7Q72L05, CAPP_THET2
Q5SKL7, CAPP_THET8P0A3X5, CAPP_THEVBP0A3X6, CAPP_THEVL
P27154, CAPP_TOBACC4L7S3, CAPP_TOLATQ3MB82, CAPP_TRIV2
A1WGR0, CAPP_VEREIB7VLL5, CAPP_VIBA3Q9KNT4, CAPP_VIBCH
Q87L54, CAPP_VIBPAQ8DCN2, CAPP_VIBVUQ7MH68, CAPP_VIBVY
Q8PP82, CAPP_XANACQ3BXC4, CAPP_XANC5Q4UR00, CAPP_XANC8
Q8P336, CAPP_XANCPQ2NZE4, CAPP_XANOMQ5GW71, CAPP_XANOR
A1JI20, CAPP_YERE8A7FCZ7, CAPP_YERP3Q1CBV8, CAPP_YERPA
B2JZD9, CAPP_YERPBQ8ZA84, CAPP_YERPEQ1CNQ7, CAPP_YERPN
A4TRH7, CAPP_YERPPQ66G74, CAPP_YERPSB1JQ63, CAPP_YERPY

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All UniProtKB/Swiss-Prot entries referenced in this entry, with possibility to download in different formats, align etc.
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 4.1.1.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 4.1.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 4.-.-.-