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ENZYME

ENZYME entry: EC 4.1.1.72

PURL: https://purl.expasy.org/enzyme/EC/4.1.1.72
Accepted Name
branched-chain-2-oxoacid decarboxylase
Alternative Name(s)
(3S)-3-methyl-2-oxopentanoate carboxy-lyase
Reaction catalysed
(S)-3-methyl-2-oxopentanoate + H(+) = 2-methylbutanal + CO2
Comment(s)
  • Acts on a number of 2-oxo acids, with a high affinity toward branched-chain substrates.
  • The aldehyde formed may be enzyme-bound, and may be an intermediate in the bacterial system for biosynthesis of branched-chain fatty acids.
Cross-references
BRENDA4.1.1.72
EC2PDB4.1.1.72
ExplorEnz4.1.1.72
KEGG Ligand Database for Enzyme Nomenclature4.1.1.72
IUBMB Enzyme Nomenclature4.1.1.72
MEDLINEFind literature relating to 4.1.1.72
MetaCyc4.1.1.72
Rhea expert-curated reactions4.1.1.72
UniProtKB/Swiss-Prot
Q06408, ARO10_YEASTP06169, PDC1_YEASTP16467, PDC5_YEAST
P26263, PDC6_YEASTQ07471, THI3_YEAST

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All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 4.1.1.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 4.1.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 4.-.-.-