A new class EC 7, Translocases, has been added to the EC list. It will be part of ENZYME from release 2018_10. Read more about EC 7 here.

ENZYME entry: EC 4.1.1.72

Accepted Name
Branched-chain-2-oxoacid decarboxylase.
Alternative Name(s)
(3S)-3-methyl-2-oxopentanoate carboxy-lyase.
Reaction catalysed
(3S)-3-methyl-2-oxopentanoate <=> 2-methylbutanal + CO(2)
Comment(s)
  • Acts on a number of 2-oxo acids, with a high affinity toward branched-chain substrates.
  • The aldehyde formed may be enzyme-bound, and may be an intermediate in the bacterial system for biosynthesis of branched-chain fatty acids.
Cross-references
BRENDA4.1.1.72
EC2PDB4.1.1.72
ExplorEnz4.1.1.72
PRIAM enzyme-specific profiles4.1.1.72
KEGG Ligand Database for Enzyme Nomenclature4.1.1.72
IUBMB Enzyme Nomenclature4.1.1.72
IntEnz4.1.1.72
MEDLINEFind literature relating to 4.1.1.72
MetaCyc4.1.1.72
UniProtKB/Swiss-Prot
Q06408, ARO10_YEAST;  P06169, PDC1_YEAST;  P16467, PDC5_YEAST;  
P26263, PDC6_YEAST;  Q07471, THI3_YEAST;  

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All UniProtKB/Swiss-Prot entries referenced in this entry, with possibility to download in different formats, align etc.
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 4.1.1.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 4.1.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 4.-.-.-