ENZYME entry: EC 4.1.1.77
Accepted Name |
2-oxo-3-hexenedioate decarboxylase.
|
Alternative Name(s) |
4-oxalocrotonate carboxy-lyase. |
4-oxalocrotonate decarboxylase. |
Reaction catalysed |
(3E)-2-oxohex-3-enedioate + H(+) <=> 2-oxopent-4-enoate + CO2 |
Comment(s) |
- Involved in the meta-cleavage pathway for the degradation of phenols,
modified phenols and catechols.
- The enzyme has been reported to accept multiple tautomeric forms.
- However, careful analysis of the stability of the different
tautomers, as well as characterization of the enzyme that produces
its substrate, EC 5.3.2.6, showed that the actual substrate for the
enzyme is (3E)-2-oxohex-3-enedioate.
|
Cross-references |
BRENDA | 4.1.1.77 |
EC2PDB | 4.1.1.77 |
ExplorEnz | 4.1.1.77 |
PRIAM enzyme-specific profiles | 4.1.1.77 |
KEGG Ligand Database for Enzyme Nomenclature | 4.1.1.77 |
IUBMB Enzyme Nomenclature | 4.1.1.77 |
IntEnz | 4.1.1.77 |
MEDLINE | Find literature relating to 4.1.1.77 |
MetaCyc | 4.1.1.77 |
Rhea expert-curated reactions | 4.1.1.77 |
UniProtKB/Swiss-Prot |
|
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ENZYME /
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