A new class EC 7, Translocases, has been added to the EC list. It will be part of ENZYME from release 2018_10. Read more about EC 7 here.

ENZYME entry: EC 4.1.1.96

Accepted Name
Carboxynorspermidine decarboxylase.
Alternative Name(s)
Carboxyspermidine decarboxylase.
Reaction catalysed
  • Carboxynorspermidine <=> bis(3-aminopropyl)amine + CO(2)
  • Carboxyspermidine <=> spermidine + CO(2)
Comment(s)
  • Part of a bacterial polyamine biosynthesis pathway.
  • The enzyme is essential for biofilm formation in the bacterium Vibrio cholerae.
  • The enzyme from Campylobacter jejuni only produces spermidine in vivo even though it shows activity with carboxynorspermidine in vitro.
Cross-references
BRENDA4.1.1.96
EC2PDB4.1.1.96
ExplorEnz4.1.1.96
PRIAM enzyme-specific profiles4.1.1.96
KEGG Ligand Database for Enzyme Nomenclature4.1.1.96
IUBMB Enzyme Nomenclature4.1.1.96
IntEnz4.1.1.96
MEDLINEFind literature relating to 4.1.1.96
MetaCyc4.1.1.96
UniProtKB/Swiss-Prot
A8FNH9, NSPC_CAMJ8;  Q5QCP2, NSPC_HERAR;  Q56575, NSPC_VIBAL;  
Q9KRL4, NSPC_VIBCH;  C6YCI2, NSPC_VIBCO;  Q8D8D2, NSPC_VIBVU;  

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All UniProtKB/Swiss-Prot entries referenced in this entry, with possibility to download in different formats, align etc.
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 4.1.1.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 4.1.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 4.-.-.-