ENZYME entry: EC 4.1.2.46
Accepted Name |
Aliphatic (R)-hydroxynitrile lyase.
|
Alternative Name(s) |
(R)-hydroxynitrile lyase. |
(R)-oxynitrilase. |
Reaction catalysed |
(2R)-2-hydroxy-2-methylbutanenitrile <=> cyanide + butan-2-one |
Cofactor(s) |
Zn(2+).
|
Comment(s) |
- The enzyme catalyzes the stereoselective synthesis of aliphatic (R)-
cyanohydrins.
- No activity toward mandelonitrile and 4-hydroxymandelonitrile.
- Natural substrates for the (R)-oxynitrilase from Linum usitatissimum
are acetone and butan-2-one, which are the building blocks of the
cyanogen glycosides in Linum, linamarin and lotaustralin,
or linustatin and neolinustatin, respectively.
- Formerly EC 4.1.2.37 and EC 4.1.2.39.
|
Cross-references |
BRENDA | 4.1.2.46 |
EC2PDB | 4.1.2.46 |
ExplorEnz | 4.1.2.46 |
PRIAM enzyme-specific profiles | 4.1.2.46 |
KEGG Ligand Database for Enzyme Nomenclature | 4.1.2.46 |
IUBMB Enzyme Nomenclature | 4.1.2.46 |
IntEnz | 4.1.2.46 |
MEDLINE | Find literature relating to 4.1.2.46 |
MetaCyc | 4.1.2.46 |
Rhea expert-curated reactions | 4.1.2.46 |
UniProtKB/Swiss-Prot |
|
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