ENZYME entry: EC 4.1.2.63
Accepted Name |
2-hydroxyacyl-CoA lyase.
|
Alternative Name(s) |
2-HPCL. |
2-hydroxyphytanoyl-CoA lyase. |
Reaction catalysed |
- A 2-hydroxy-3-methyl-C(n)-fatty-acyl-CoA <=> a 2-methyl-branched C(n-1)-fatty aldehyde + formyl-CoA
- A (2R)-2-hydroxy-C(n)-long-chain fatty acyl-CoA <=> a C(n-1)-long-chain fatty aldehyde + formyl-CoA
|
Cofactor(s) |
Mg(2+); Thiamine diphosphate.
|
Comment(s) |
- This peroxisomal enzyme, found in animals, is involved in the alpha-
oxidation of 3-methyl-branched fatty acids like phytanic acid and the
shortening of 2-hydroxy long-chain fatty acids.
- Formerly EC 4.1.2.n2.
|
Cross-references |
BRENDA | 4.1.2.63 |
EC2PDB | 4.1.2.63 |
ExplorEnz | 4.1.2.63 |
PRIAM enzyme-specific profiles | 4.1.2.63 |
KEGG Ligand Database for Enzyme Nomenclature | 4.1.2.63 |
IUBMB Enzyme Nomenclature | 4.1.2.63 |
IntEnz | 4.1.2.63 |
MEDLINE | Find literature relating to 4.1.2.63 |
MetaCyc | 4.1.2.63 |
Rhea expert-curated reactions | 4.1.2.63 |
UniProtKB/Swiss-Prot |
|
View entry in original ENZYME format
View entry in raw text format (no links)
All
ENZYME /
UniProtKB/Swiss-Prot entries corresponding to 4.1.2.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 4.1.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 4.-.-.-