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ENZYME

ENZYME entry: EC 4.1.3.16

PURL: https://purl.expasy.org/enzyme/EC/4.1.3.16
Accepted Name
4-hydroxy-2-oxoglutarate aldolase
Alternative Name(s)
2-keto-4-hydroxyglutarate aldolase
2-oxo-4-hydroxyglutarate aldolase
4-hydroxy-2-oxoglutarate glyoxylate-lyase
KHGA
KHG-aldolase
Reaction catalysed
  • (4R)-4-hydroxy-2-oxoglutarate = glyoxylate + pyruvate
  • (4S)-4-hydroxy-2-oxoglutarate = glyoxylate + pyruvate
Comment(s)
  • The enzymes from rat liver and bovine liver act on both enantiomers of 4-hydroxy-2-oxoglutarate.
  • Formerly EC 4.1.2.1 and EC 4.1.2.31.
Cross-references
BRENDA4.1.3.16
EC2PDB4.1.3.16
ExplorEnz4.1.3.16
KEGG Ligand Database for Enzyme Nomenclature4.1.3.16
IUBMB Enzyme Nomenclature4.1.3.16
MEDLINEFind literature relating to 4.1.3.16
MetaCyc4.1.3.16
Rhea expert-curated reactions4.1.3.16
UniProtKB/Swiss-Prot
Q9AQI0, HMGA_PSEOCQ0P5I5, HOGA1_BOVINP0CL20, HOGA1_COCIM
Q6NY77, HOGA1_DANREQ5BD77, HOGA1_EMENIQ86XE5, HOGA1_HUMAN
Q9DCU9, HOGA1_MOUSEQ5XGL6, HOGA1_XENLAQ5M8W9, HOGA1_XENTR

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All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 4.1.3.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 4.1.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 4.-.-.-