ENZYME entry: EC 4.1.3.24
| Accepted Name |
|---|
| malyl-CoA lyase.
|
| Alternative Name(s) |
|---|
| (3S)-3-carboxy-3-hydroxypropanoyl-CoA glyoxylate-lyase. |
| L-malyl-CoA lyase. |
| malyl-coenzyme A lyase. |
| Reaction catalysed |
|---|
- (S)-malyl-CoA <=> acetyl-CoA + glyoxylate
- (2R,3S)-beta-methylmalyl-CoA <=> glyoxylate + propanoyl-CoA
|
| Comment(s) |
|---|
- The enzymes from Rhodobacter species catalyze a step in the
ethylmalonyl-CoA pathway for acetate assimilation.
- The enzyme from halophilic bacteria participate in the
methylaspartate cycle and catalyze the reaction in the direction of
malyl-CoA formation.
- The enzyme from the bacterium Chloroflexus aurantiacus, which
participates in the 3-hydroxypropanoate cycle for carbon
assimilation, also has the activity of EC 4.1.3.25.
|
| Cross-references |
|---|
| BRENDA | 4.1.3.24 |
| EC2PDB | 4.1.3.24 |
| ExplorEnz | 4.1.3.24 |
| PRIAM enzyme-specific profiles | 4.1.3.24 |
| KEGG Ligand Database for Enzyme Nomenclature | 4.1.3.24 |
| IUBMB Enzyme Nomenclature | 4.1.3.24 |
| IntEnz | 4.1.3.24 |
| MEDLINE | Find literature relating to 4.1.3.24 |
| MetaCyc | 4.1.3.24 |
| Rhea expert-curated reactions | 4.1.3.24 |
| UniProtKB/Swiss-Prot |
| Q5V0X0, AMASY_HALMA; | A3PGR7, MCAL_CERS1; | Q3J5L6, MCAL_CERS4; |
| A4WVF5, MCAL_CERS5; | B9KLE8, MCAL_CERSK; | Q5V463, MCAL_HALMA; |
| B6E2X2, MCAL_RHOCA; | D5AR83, MCAL_RHOCB; | A9WC35, MCLA_CHLAA; |
| S5N020, MCLA_CHLAU; |
|
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