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ENZYME

ENZYME entry: EC 4.1.3.24

PURL: https://purl.expasy.org/enzyme/EC/4.1.3.24
Accepted Name
malyl-CoA lyase
Alternative Name(s)
(3S)-3-carboxy-3-hydroxypropanoyl-CoA glyoxylate-lyase
L-malyl-CoA lyase
malyl-coenzyme A lyase
Reaction catalysed
  • (S)-malyl-CoA = glyoxylate + acetyl-CoA
  • (2R,3S)-beta-methylmalyl-CoA = propanoyl-CoA + glyoxylate
Comment(s)
  • The enzymes from Rhodobacter species catalyze a step in the ethylmalonyl-CoA pathway for acetate assimilation.
  • The enzyme from halophilic bacteria participate in the methylaspartate cycle and catalyze the reaction in the direction of malyl-CoA formation.
  • The enzyme from the bacterium Chloroflexus aurantiacus, which participates in the 3-hydroxypropanoate cycle for carbon assimilation, also has the activity of EC 4.1.3.25.
Cross-references
BRENDA4.1.3.24
EC2PDB4.1.3.24
ExplorEnz4.1.3.24
KEGG Ligand Database for Enzyme Nomenclature4.1.3.24
IUBMB Enzyme Nomenclature4.1.3.24
MEDLINEFind literature relating to 4.1.3.24
MetaCyc4.1.3.24
Rhea expert-curated reactions4.1.3.24
UniProtKB/Swiss-Prot
Q5V0X0, AMASY_HALMAA3PGR7, MCAL_CERS1Q3J5L6, MCAL_CERS4
A4WVF5, MCAL_CERS5B9KLE8, MCAL_CERSKQ5V463, MCAL_HALMA
B6E2X2, MCAL_RHOCAD5AR83, MCAL_RHOCBA9WC35, MCLA_CHLAA
S5N020, MCLA_CHLAU

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All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 4.1.3.-
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