Expasy logo

ENZYME

ENZYME entry: EC 4.1.3.3

Accepted Name
N-acetylneuraminate lyase
Alternative Name(s)
N-acetylneuraminate pyruvate-lyase
N-acetylneuraminic acid aldolase
Reaction catalysed
aceneuramate <=> N-acetyl-D-mannosamine + pyruvate
Comment(s)
  • This enzyme is involved in the degradation of N-acetylneuraminate.
  • It is specific for the open form of the sugar.
  • It also acts on N-glycoloylneuraminate and on O-acetylated sialic acids, other than 4-O-acetylated derivatives.
Cross-references
BRENDA4.1.3.3
EC2PDB4.1.3.3
ExplorEnz4.1.3.3
PRIAM enzyme-specific profiles4.1.3.3
KEGG Ligand Database for Enzyme Nomenclature4.1.3.3
IUBMB Enzyme Nomenclature4.1.3.3
IntEnz4.1.3.3
MEDLINEFind literature relating to 4.1.3.3
MetaCyc4.1.3.3
Rhea expert-curated reactions4.1.3.3
UniProtKB/Swiss-Prot
Q8FD58, NANA1_ECOL6Q8FDU7, NANA2_ECOL6A3N352, NANA_ACTP2
B3GZ05, NANA_ACTP7B0BSI2, NANA_ACTPJA8AQB6, NANA_CITK8
Q0TUP8, NANA_CLOP1Q9S4K9, NANA_CLOPEQ0SWI8, NANA_CLOPS
A7ZSB8, NANA_ECO24B7UJV8, NANA_ECO27B7MBY7, NANA_ECO45
B7LHT3, NANA_ECO55P0A6L5, NANA_ECO57B5YSV2, NANA_ECO5E
B7NKT6, NANA_ECO7IB7M0T7, NANA_ECO8AC4ZSW3, NANA_ECOBW
B1XHJ8, NANA_ECODHA8A535, NANA_ECOHSA1AGB9, NANA_ECOK1
Q0TCP1, NANA_ECOL5B1IQQ4, NANA_ECOLCP0A6L4, NANA_ECOLI
B6I1U3, NANA_ECOSEB1LGJ0, NANA_ECOSMQ1R6B5, NANA_ECOUT
A4WF38, NANA_ENT38B7LRJ3, NANA_ESCF3Q8RDN6, NANA_FUSNN
P44539, NANA_HAEINQ0I2T8, NANA_HISS1B0UTI7, NANA_HISS2
P59407, NANA_LACPLQ9CKB0, NANA_PASMUQ92WP0, NANA_RHIME
B5F7J9, NANA_SALA4A9MNY6, NANA_SALARQ57JC9, NANA_SALCH
B5FIR8, NANA_SALDCB5R0L2, NANA_SALEPB5RET7, NANA_SALG2
B4TJR3, NANA_SALHSB4T750, NANA_SALNSQ5PLE9, NANA_SALPA
A9N833, NANA_SALPBC0PZN4, NANA_SALPCB5BGP5, NANA_SALPK
B4TWJ0, NANA_SALSVQ8Z3F0, NANA_SALTIQ8ZLQ6, NANA_SALTY
B2U1V9, NANA_SHIB3Q31W94, NANA_SHIBSQ32BB4, NANA_SHIDS
Q0T065, NANA_SHIF8P0A6L6, NANA_SHIFLQ3YX23, NANA_SHISS
A7WXZ2, NANA_STAA1A6TY99, NANA_STAA2Q2FJU9, NANA_STAA3
Q2G160, NANA_STAA8A5IPI2, NANA_STAA9Q2YVB1, NANA_STAAB
Q5HJ53, NANA_STAACA6QDU7, NANA_STAAEP63949, NANA_STAAM
P99123, NANA_STAANQ6GK01, NANA_STAARQ6GCF6, NANA_STAAS
A8YZD9, NANA_STAATQ8NYC7, NANA_STAAWB9DIJ2, NANA_STACT
Q4L9T4, NANA_STAHJQ3B8E8, NPLA_XENLAQ5XGL8, NPLB_XENLA
Q29RY9, NPL_BOVINQ5ZKD4, NPL_CHICKQ6NYR8, NPL_DANRE
Q9BXD5, NPL_HUMANQ9DCJ9, NPL_MOUSEQ9BEC7, NPL_PIG
Q5RDY1, NPL_PONABQ66H59, NPL_RATQ5M905, NPL_XENTR

View entry in original ENZYME format
View entry in raw text format (no links)
All UniProtKB/Swiss-Prot entries referenced in this entry, with possibility to download in different formats, align etc.
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 4.1.3.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 4.1.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 4.-.-.-