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ENZYME

ENZYME entry: EC 4.1.3.3

PURL: https://purl.expasy.org/enzyme/EC/4.1.3.3
Accepted Name
N-acetylneuraminate lyase
Alternative Name(s)
N-acetylneuraminate pyruvate-lyase
N-acetylneuraminic acid aldolase
Reaction catalysed
aceneuramate = aldehydo-N-acetyl-D-mannosamine + pyruvate
Comment(s)
  • This enzyme is involved in the degradation of N-acetylneuraminate.
  • It is specific for the open form of the sugar.
  • It also acts on N-glycoloylneuraminate and on O-acetylated sialic acids, other than 4-O-acetylated derivatives.
Cross-references
BRENDA4.1.3.3
EC2PDB4.1.3.3
ExplorEnz4.1.3.3
KEGG Ligand Database for Enzyme Nomenclature4.1.3.3
IUBMB Enzyme Nomenclature4.1.3.3
MEDLINEFind literature relating to 4.1.3.3
MetaCyc4.1.3.3
Rhea expert-curated reactions4.1.3.3
UniProtKB/Swiss-Prot
Q8FD58, NANA1_ECOL6Q8FDU7, NANA2_ECOL6A3N352, NANA_ACTP2
B3GZ05, NANA_ACTP7B0BSI2, NANA_ACTPJA8AQB6, NANA_CITK8
Q0TUP8, NANA_CLOP1Q9S4K9, NANA_CLOPEQ0SWI8, NANA_CLOPS
A7ZSB8, NANA_ECO24B7UJV8, NANA_ECO27B7MBY7, NANA_ECO45
B7LHT3, NANA_ECO55P0A6L5, NANA_ECO57B5YSV2, NANA_ECO5E
B7NKT6, NANA_ECO7IB7M0T7, NANA_ECO8AC4ZSW3, NANA_ECOBW
B1XHJ8, NANA_ECODHA8A535, NANA_ECOHSA1AGB9, NANA_ECOK1
Q0TCP1, NANA_ECOL5B1IQQ4, NANA_ECOLCP0A6L4, NANA_ECOLI
B6I1U3, NANA_ECOSEB1LGJ0, NANA_ECOSMQ1R6B5, NANA_ECOUT
A4WF38, NANA_ENT38B7LRJ3, NANA_ESCF3Q8RDN6, NANA_FUSNN
P44539, NANA_HAEINQ0I2T8, NANA_HISS1B0UTI7, NANA_HISS2
P59407, NANA_LACPLA7B555, NANA_MEDG7Q9CKB0, NANA_PASMU
Q92WP0, NANA_RHIMEB5F7J9, NANA_SALA4A9MNY6, NANA_SALAR
Q57JC9, NANA_SALCHB5FIR8, NANA_SALDCB5R0L2, NANA_SALEP
B5RET7, NANA_SALG2B4TJR3, NANA_SALHSB4T750, NANA_SALNS
Q5PLE9, NANA_SALPAA9N833, NANA_SALPBC0PZN4, NANA_SALPC
B5BGP5, NANA_SALPKB4TWJ0, NANA_SALSVQ8Z3F0, NANA_SALTI
Q8ZLQ6, NANA_SALTYB2U1V9, NANA_SHIB3Q31W94, NANA_SHIBS
Q32BB4, NANA_SHIDSQ0T065, NANA_SHIF8P0A6L6, NANA_SHIFL
Q3YX23, NANA_SHISSA7WXZ2, NANA_STAA1A6TY99, NANA_STAA2
Q2FJU9, NANA_STAA3Q2G160, NANA_STAA8A5IPI2, NANA_STAA9
Q2YVB1, NANA_STAABQ5HJ53, NANA_STAACA6QDU7, NANA_STAAE
P63949, NANA_STAAMP99123, NANA_STAANQ6GK01, NANA_STAAR
Q6GCF6, NANA_STAASA8YZD9, NANA_STAATQ8NYC7, NANA_STAAW
B9DIJ2, NANA_STACTQ4L9T4, NANA_STAHJQ3B8E8, NPLA_XENLA
Q5XGL8, NPLB_XENLAQ29RY9, NPL_BOVINQ5ZKD4, NPL_CHICK
Q6NYR8, NPL_DANREQ9BXD5, NPL_HUMANQ9DCJ9, NPL_MOUSE
Q9BEC7, NPL_PIGQ5RDY1, NPL_PONABQ66H59, NPL_RAT
Q5M905, NPL_XENTR

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All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 4.1.3.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 4.1.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 4.-.-.-