A new class EC 7, Translocases, has been added to the EC list. It will be part of ENZYME from release 2018_10. Read more about EC 7 here.

ENZYME entry: EC 4.1.99.3

Accepted Name
Deoxyribodipyrimidine photo-lyase.
Alternative Name(s)
DNA photolyase.
Photoreactivating enzyme.
Reaction catalysed
Cyclobutadipyrimidine (in DNA) <=> 2 pyrimidine residues (in DNA)
Cofactor(s)
5,10-methenyltetrahydrofolate; FAD.
Comment(s)
  • A flavoprotein containing a second chromophore group.
  • Catalyzes the reactivation by light of irradiated DNA.
  • A similar reactivation of irradiated RNA is probably due to a separate enzyme.
Cross-references
PROSITEPDOC00331 ; PDOC00832
BRENDA4.1.99.3
EC2PDB4.1.99.3
ExplorEnz4.1.99.3
PRIAM enzyme-specific profiles4.1.99.3
KEGG Ligand Database for Enzyme Nomenclature4.1.99.3
IUBMB Enzyme Nomenclature4.1.99.3
IntEnz4.1.99.3
MEDLINEFind literature relating to 4.1.99.3
MetaCyc4.1.99.3
UniProtKB/Swiss-Prot
A9CJC9, PHRA_AGRFC;  Q9SB00, PHR_ARATH;  Q04449, PHR_BACPE;  
P57386, PHR_BUCAI;  Q89AJ9, PHR_BUCBP;  P34205, PHR_CARAU;  
P00914, PHR_ECOLI;  Q9HQ46, PHR_HALSA;  P12769, PHR_METTH;  
P58818, PHR_METTM;  P27526, PHR_NEUCR;  Q6F6A2, PHR_ORYSJ;  
Q28811, PHR_POTTR;  P25078, PHR_SALTY;  P12768, PHR_STRGR;  
P05327, PHR_SYNP6;  Q55081, PHR_SYNY3;  P61496, PHR_THET2;  
P61497, PHR_THET8;  Q9KNA8, PHR_VIBCH;  P05066, PHR_YEAST;  

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