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ENZYME

ENZYME entry: EC 4.2.1.116

PURL: https://purl.expasy.org/enzyme/EC/4.2.1.116
Accepted Name
3-hydroxypropionyl-CoA dehydratase
Alternative Name(s)
3-hydroxypropanoate-CoA dehydratase
3-hydroxypropionyl-CoA hydro-lyase
Reaction catalysed
3-hydroxypropanoyl-CoA = acryloyl-CoA + H2O
Comment(s)
  • Catalyzes a step in the 3-hydroxypropanoate/4-hydroxybutyrate cycle, an autotrophic CO2 fixation pathway found in some thermoacidophilic archaea.
  • The enzyme from Metallosphaera sedula acts nearly equally as well on (S)-3-hydroxybutanoyl-CoA but not (R)-3-hydroxybutanoyl-CoA.
Cross-references
BRENDA4.2.1.116
EC2PDB4.2.1.116
ExplorEnz4.2.1.116
KEGG Ligand Database for Enzyme Nomenclature4.2.1.116
IUBMB Enzyme Nomenclature4.2.1.116
MEDLINEFind literature relating to 4.2.1.116
MetaCyc4.2.1.116
Rhea expert-curated reactions4.2.1.116
UniProtKB/Swiss-Prot
A4YI89, HPCD_METS5

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