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ENZYME

ENZYME class: 4.2.1.-


Release of 13-Sep-23

4.-.-.-: Lyases
4.2.-.-: Carbon-oxygen lyases
4.2.1.-: Hydro-lyases

All UniProtKB/Swiss-Prot entries corresponding to class 4.2.1.-.

The following ENZYME entries belong to class 4.2.1.-:

4.2.1.1carbonic anhydrase
4.2.1.2fumarate hydratase
4.2.1.3aconitate hydratase
4.2.1.4Transferred entry: 4.2.1.3
4.2.1.5arabinonate dehydratase
4.2.1.6galactonate dehydratase
4.2.1.7altronate dehydratase
4.2.1.8mannonate dehydratase
4.2.1.9dihydroxy-acid dehydratase
4.2.1.103-dehydroquinate dehydratase
4.2.1.11phosphopyruvate hydratase
4.2.1.12phosphogluconate dehydratase
4.2.1.13Transferred entry: 4.3.1.17
4.2.1.14Transferred entry: 4.3.1.18
4.2.1.15Transferred entry: 4.4.1.1
4.2.1.16Transferred entry: 4.3.1.19
4.2.1.17enoyl-CoA hydratase
4.2.1.18methylglutaconyl-CoA hydratase
4.2.1.19imidazoleglycerol-phosphate dehydratase
4.2.1.20tryptophan synthase
4.2.1.21Transferred entry: 4.2.1.22
4.2.1.22cystathionine beta-synthase
4.2.1.23Deleted entry
4.2.1.24porphobilinogen synthase
4.2.1.25L-arabinonate dehydratase
4.2.1.26Transferred entry: 4.3.1.9
4.2.1.27acetylenecarboxylate hydratase
4.2.1.28propanediol dehydratase
4.2.1.29Transferred entry: 4.99.1.6
4.2.1.30glycerol dehydratase
4.2.1.31maleate hydratase
4.2.1.32L(+)-tartrate dehydratase
4.2.1.333-isopropylmalate dehydratase
4.2.1.34(S)-2-methylmalate dehydratase
4.2.1.35(R)-2-methylmalate dehydratase
4.2.1.36homoaconitate hydratase
4.2.1.37Transferred entry: 3.3.2.4
4.2.1.38Transferred entry: 4.3.1.20
4.2.1.39gluconate dehydratase
4.2.1.40glucarate dehydratase
4.2.1.415-dehydro-4-deoxyglucarate dehydratase
4.2.1.42galactarate dehydratase
4.2.1.432-dehydro-3-deoxy-L-arabinonate dehydratase
4.2.1.44myo-inosose-2 dehydratase
4.2.1.45CDP-glucose 4,6-dehydratase
4.2.1.46dTDP-glucose 4,6-dehydratase
4.2.1.47GDP-mannose 4,6-dehydratase
4.2.1.48D-glutamate cyclase
4.2.1.49urocanate hydratase
4.2.1.50pyrazolylalanine synthase
4.2.1.51prephenate dehydratase
4.2.1.52Transferred entry: 4.3.3.7
4.2.1.53oleate hydratase
4.2.1.54lactoyl-CoA dehydratase
4.2.1.553-hydroxybutyryl-CoA dehydratase
4.2.1.56itaconyl-CoA hydratase
4.2.1.57isohexenylglutaconyl-CoA hydratase
4.2.1.58Transferred entry: 4.2.1.59
4.2.1.593-hydroxyacyl-[acyl-carrier-protein] dehydratase
4.2.1.60Transferred entry: 4.2.1.59
4.2.1.61Transferred entry: 4.2.1.59
4.2.1.625alpha-hydroxysteroid dehydratase
4.2.1.63Transferred entry: 3.3.2.9 and 3.3.2.10
4.2.1.64Transferred entry: 3.3.2.9 and 3.3.2.10
4.2.1.653-cyanoalanine hydratase
4.2.1.66cyanide hydratase
4.2.1.67D-fuconate dehydratase
4.2.1.68L-fuconate dehydratase
4.2.1.69cyanamide hydratase
4.2.1.70pseudouridylate synthase
4.2.1.71Transferred entry: 4.2.1.27
4.2.1.72Transferred entry: 4.1.1.78
4.2.1.73protoaphin-aglucone dehydratase (cyclizing)
4.2.1.74medium-chain-enoyl-CoA hydratase
4.2.1.75uroporphyrinogen-III synthase
4.2.1.76UDP-glucose 4,6-dehydratase
4.2.1.77trans-L-3-hydroxyproline dehydratase
4.2.1.78(S)-norcoclaurine synthase
4.2.1.792-methylcitrate dehydratase
4.2.1.802-oxopent-4-enoate hydratase
4.2.1.81D(-)-tartrate dehydratase
4.2.1.82xylonate dehydratase
4.2.1.834-oxalmesaconate hydratase
4.2.1.84nitrile hydratase
4.2.1.85dimethylmaleate hydratase
4.2.1.86Transferred entry: 4.2.1.98
4.2.1.87octopamine dehydratase
4.2.1.88synephrine dehydratase
4.2.1.89Transferred entry: 2.8.3.21 and 4.2.1.149
4.2.1.90L-rhamnonate dehydratase
4.2.1.91arogenate dehydratase
4.2.1.92hydroperoxide dehydratase
4.2.1.93ATP-dependent NAD(P)H-hydrate dehydratase
4.2.1.94scytalone dehydratase
4.2.1.95kievitone hydratase
4.2.1.964a-hydroxytetrahydrobiopterin dehydratase
4.2.1.97phaseollidin hydratase
4.2.1.9816alpha-hydroxyprogesterone dehydratase
4.2.1.992-methylisocitrate dehydratase
4.2.1.100cyclohexa-1,5-dienecarbonyl-CoA hydratase
4.2.1.101Transferred entry: 4.1.2.61
4.2.1.102Transferred entry: 4.2.1.100
4.2.1.103cyclohexyl-isocyanide hydratase
4.2.1.104cyanase
4.2.1.1052-hydroxyisoflavanone dehydratase
4.2.1.106bile-acid 7alpha-dehydratase
4.2.1.1073alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-enoyl-CoA hydratase
4.2.1.108ectoine synthase
4.2.1.109methylthioribulose 1-phosphate dehydratase
4.2.1.110aldos-2-ulose dehydratase
4.2.1.1111,5-anhydro-D-fructose dehydratase
4.2.1.112acetylene hydratase
4.2.1.113o-succinylbenzoate synthase
4.2.1.114methanogen homoaconitase
4.2.1.115UDP-N-acetylglucosamine 4,6-dehydratase (inverting)
4.2.1.1163-hydroxypropionyl-CoA dehydratase
4.2.1.1172-methylcitrate dehydratase (2-methyl-trans-aconitate forming)
4.2.1.1183-dehydroshikimate dehydratase
4.2.1.119enoyl-CoA hydratase 2
4.2.1.1204-hydroxybutanoyl-CoA dehydratase
4.2.1.121colneleate synthase
4.2.1.122tryptophan synthase (indole-salvaging)
4.2.1.123tetrahymanol synthase
4.2.1.124arabidiol synthase
4.2.1.125dammarenediol II synthase
4.2.1.126N-acetylmuramic acid 6-phosphate etherase
4.2.1.127linalool dehydratase
4.2.1.128lupan-3beta,20-diol synthase
4.2.1.129squalene--hopanol cyclase
4.2.1.130D-lactate dehydratase
4.2.1.131carotenoid 1,2-hydratase
4.2.1.1322-hydroxyhexa-2,4-dienoate hydratase
4.2.1.133copal-8-ol diphosphate hydratase
4.2.1.134very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase
4.2.1.135UDP-N-acetylglucosamine 4,6-dehydratase (configuration-retaining)
4.2.1.136ADP-dependent NAD(P)H-hydrate dehydratase
4.2.1.137sporulenol synthase
4.2.1.138(+)-caryolan-1-ol synthase
4.2.1.139pterocarpan synthase
4.2.1.140gluconate/galactonate dehydratase
4.2.1.1412-dehydro-3-deoxy-D-arabinonate dehydratase
4.2.1.1425'-oxoaverantin cyclase
4.2.1.143versicolorin B synthase
4.2.1.1443-amino-5-hydroxybenzoate synthase
4.2.1.145capreomycidine synthase
4.2.1.146L-galactonate dehydratase
4.2.1.1475,6,7,8-tetrahydromethanopterin hydro-lyase
4.2.1.1482-methylfumaryl-CoA hydratase
4.2.1.149crotonobetainyl-CoA hydratase
4.2.1.150short-chain-enoyl-CoA hydratase
4.2.1.151chorismate dehydratase
4.2.1.152hydroperoxy icosatetraenoate dehydratase
4.2.1.1533-methylfumaryl-CoA hydratase
4.2.1.154tetracenomycin F2 cyclase
4.2.1.155methylthioacryloyl-CoA hydratase
4.2.1.156L-talarate dehydratase
4.2.1.157(R)-2-hydroxyisocaproyl-CoA dehydratase
4.2.1.158galactarate dehydratase (D-threo-forming)
4.2.1.159dTDP-4-dehydro-6-deoxy-alpha-D-glucopyranose 2,3-dehydratase
4.2.1.1602,5-diamino-6-(5-phospho-D-ribosylamino)pyrimidin-4(3H)-one
4.2.1.160isomerase/dehydratase
4.2.1.161bisanhydrobacterioruberin hydratase
4.2.1.1626-deoxy-6-sulfo-D-gluconate dehydratase
4.2.1.1632-oxo-hept-4-ene-1,7-dioate hydratase
4.2.1.164dTDP-4-dehydro-2,6-dideoxy-D-glucose 3-dehydratase
4.2.1.165chlorophyllide a 3(1)-hydratase
4.2.1.166phosphinomethylmalate isomerase
4.2.1.167(R)-2-hydroxyglutaryl-CoA dehydratase
4.2.1.168GDP-4-dehydro-6-deoxy-alpha-D-mannose 3-dehydratase
4.2.1.1693-vinylbacteriochlorophyllide d 3(1)-hydratase
4.2.1.1702-(omega-methylthio)alkylmalate dehydratase
4.2.1.171cis-L-3-hydroxyproline dehydratase
4.2.1.172trans-4-hydroxy-L-proline dehydratase
4.2.1.173ent-8alpha-hydroxylabd-13-en-15-yl diphosphate synthase
4.2.1.174peregrinol diphosphate synthase
4.2.1.175(R)-3-(aryl)lactoyl-CoA dehydratase
4.2.1.176L-lyxonate dehydratase
4.2.1.177(2S)-3-sulfopropanediol dehydratase
4.2.1.178difructose-dianhydride-III synthase
4.2.1.179difructose-anhydride-I synthase
4.2.1.180(E)-benzylidenesuccinyl-CoA hydratase
4.2.1.n1Transferred entry: 4.2.1.126
4.2.1.n2Transferred entry: 4.2.1.134