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ENZYME class: 4.2.1

Release of 12-Oct-22


Lyases
Carbon-oxygen lyases
Hydro-lyases

All UniProtKB/Swiss-Prot entries corresponding to class 4.2.1.-.

The following ENZYME entries belong to class 4.2.1.-:

4.2.1.1      carbonic anhydrase
4.2.1.2      fumarate hydratase
4.2.1.3      aconitate hydratase
4.2.1.4      Transferred entry: 4.2.1.3
4.2.1.5      arabinonate dehydratase
4.2.1.6      galactonate dehydratase
4.2.1.7      altronate dehydratase
4.2.1.8      mannonate dehydratase
4.2.1.9      dihydroxy-acid dehydratase
4.2.1.10     3-dehydroquinate dehydratase
4.2.1.11     phosphopyruvate hydratase
4.2.1.12     phosphogluconate dehydratase
4.2.1.13     Transferred entry: 4.3.1.17
4.2.1.14     Transferred entry: 4.3.1.18
4.2.1.15     Transferred entry: 4.4.1.1
4.2.1.16     Transferred entry: 4.3.1.19
4.2.1.17     enoyl-CoA hydratase
4.2.1.18     methylglutaconyl-CoA hydratase
4.2.1.19     imidazoleglycerol-phosphate dehydratase
4.2.1.20     tryptophan synthase
4.2.1.21     Transferred entry: 4.2.1.22
4.2.1.22     cystathionine beta-synthase
4.2.1.23     Deleted entry
4.2.1.24     porphobilinogen synthase
4.2.1.25     L-arabinonate dehydratase
4.2.1.26     Transferred entry: 4.3.1.9
4.2.1.27     acetylenecarboxylate hydratase
4.2.1.28     propanediol dehydratase
4.2.1.29     Transferred entry: 4.99.1.6
4.2.1.30     glycerol dehydratase
4.2.1.31     maleate hydratase
4.2.1.32     L(+)-tartrate dehydratase
4.2.1.33     3-isopropylmalate dehydratase
4.2.1.34     (S)-2-methylmalate dehydratase
4.2.1.35     (R)-2-methylmalate dehydratase
4.2.1.36     homoaconitate hydratase
4.2.1.37     Transferred entry: 3.3.2.4
4.2.1.38     Transferred entry: 4.3.1.20
4.2.1.39     gluconate dehydratase
4.2.1.40     glucarate dehydratase
4.2.1.41     5-dehydro-4-deoxyglucarate dehydratase
4.2.1.42     galactarate dehydratase
4.2.1.43     2-dehydro-3-deoxy-L-arabinonate dehydratase
4.2.1.44     myo-inosose-2 dehydratase
4.2.1.45     CDP-glucose 4,6-dehydratase
4.2.1.46     dTDP-glucose 4,6-dehydratase
4.2.1.47     GDP-mannose 4,6-dehydratase
4.2.1.48     D-glutamate cyclase
4.2.1.49     urocanate hydratase
4.2.1.50     pyrazolylalanine synthase
4.2.1.51     prephenate dehydratase
4.2.1.52     Transferred entry: 4.3.3.7
4.2.1.53     oleate hydratase
4.2.1.54     lactoyl-CoA dehydratase
4.2.1.55     3-hydroxybutyryl-CoA dehydratase
4.2.1.56     itaconyl-CoA hydratase
4.2.1.57     isohexenylglutaconyl-CoA hydratase
4.2.1.58     Transferred entry: 4.2.1.59
4.2.1.59     3-hydroxyacyl-[acyl-carrier-protein] dehydratase
4.2.1.60     Transferred entry: 4.2.1.59
4.2.1.61     Transferred entry: 4.2.1.59
4.2.1.62     5alpha-hydroxysteroid dehydratase
4.2.1.63     Transferred entry: 3.3.2.9 and 3.3.2.10
4.2.1.64     Transferred entry: 3.3.2.9 and 3.3.2.10
4.2.1.65     3-cyanoalanine hydratase
4.2.1.66     cyanide hydratase
4.2.1.67     D-fuconate dehydratase
4.2.1.68     L-fuconate dehydratase
4.2.1.69     cyanamide hydratase
4.2.1.70     pseudouridylate synthase
4.2.1.71     Transferred entry: 4.2.1.27
4.2.1.72     Transferred entry: 4.1.1.78
4.2.1.73     protoaphin-aglucone dehydratase (cyclizing)
4.2.1.74     medium-chain-enoyl-CoA hydratase
4.2.1.75     uroporphyrinogen-III synthase
4.2.1.76     UDP-glucose 4,6-dehydratase
4.2.1.77     trans-L-3-hydroxyproline dehydratase
4.2.1.78     (S)-norcoclaurine synthase
4.2.1.79     2-methylcitrate dehydratase
4.2.1.80     2-oxopent-4-enoate hydratase
4.2.1.81     D(-)-tartrate dehydratase
4.2.1.82     xylonate dehydratase
4.2.1.83     4-oxalmesaconate hydratase
4.2.1.84     nitrile hydratase
4.2.1.85     dimethylmaleate hydratase
4.2.1.86     Transferred entry: 4.2.1.98
4.2.1.87     octopamine dehydratase
4.2.1.88     synephrine dehydratase
4.2.1.89     Transferred entry: 2.8.3.21 and 4.2.1.149
4.2.1.90     L-rhamnonate dehydratase
4.2.1.91     arogenate dehydratase
4.2.1.92     hydroperoxide dehydratase
4.2.1.93     ATP-dependent NAD(P)H-hydrate dehydratase
4.2.1.94     scytalone dehydratase
4.2.1.95     kievitone hydratase
4.2.1.96     4a-hydroxytetrahydrobiopterin dehydratase
4.2.1.97     phaseollidin hydratase
4.2.1.98     16alpha-hydroxyprogesterone dehydratase
4.2.1.99     2-methylisocitrate dehydratase
4.2.1.100    cyclohexa-1,5-dienecarbonyl-CoA hydratase
4.2.1.101    Transferred entry: 4.1.2.61
4.2.1.102    Transferred entry: 4.2.1.100
4.2.1.103    cyclohexyl-isocyanide hydratase
4.2.1.104    cyanase
4.2.1.105    2-hydroxyisoflavanone dehydratase
4.2.1.106    bile-acid 7alpha-dehydratase
4.2.1.107    3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-enoyl-CoA hydratase
4.2.1.108    ectoine synthase
4.2.1.109    methylthioribulose 1-phosphate dehydratase
4.2.1.110    aldos-2-ulose dehydratase
4.2.1.111    1,5-anhydro-D-fructose dehydratase
4.2.1.112    acetylene hydratase
4.2.1.113    o-succinylbenzoate synthase
4.2.1.114    methanogen homoaconitase
4.2.1.115    UDP-N-acetylglucosamine 4,6-dehydratase (inverting)
4.2.1.116    3-hydroxypropionyl-CoA dehydratase
4.2.1.117    2-methylcitrate dehydratase (2-methyl-trans-aconitate forming)
4.2.1.118    3-dehydroshikimate dehydratase
4.2.1.119    enoyl-CoA hydratase 2
4.2.1.120    4-hydroxybutanoyl-CoA dehydratase
4.2.1.121    colneleate synthase
4.2.1.122    tryptophan synthase (indole-salvaging)
4.2.1.123    tetrahymanol synthase
4.2.1.124    arabidiol synthase
4.2.1.125    dammarenediol II synthase
4.2.1.126    N-acetylmuramic acid 6-phosphate etherase
4.2.1.127    linalool dehydratase
4.2.1.128    lupan-3beta,20-diol synthase
4.2.1.129    squalene--hopanol cyclase
4.2.1.130    D-lactate dehydratase
4.2.1.131    carotenoid 1,2-hydratase
4.2.1.132    2-hydroxyhexa-2,4-dienoate hydratase
4.2.1.133    copal-8-ol diphosphate hydratase
4.2.1.134    very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase
4.2.1.135    UDP-N-acetylglucosamine 4,6-dehydratase (configuration-retaining)
4.2.1.136    ADP-dependent NAD(P)H-hydrate dehydratase
4.2.1.137    sporulenol synthase
4.2.1.138    (+)-caryolan-1-ol synthase
4.2.1.139    pterocarpan synthase
4.2.1.140    gluconate/galactonate dehydratase
4.2.1.141    2-dehydro-3-deoxy-D-arabinonate dehydratase
4.2.1.142    5'-oxoaverantin cyclase
4.2.1.143    versicolorin B synthase
4.2.1.144    3-amino-5-hydroxybenzoate synthase
4.2.1.145    capreomycidine synthase
4.2.1.146    L-galactonate dehydratase
4.2.1.147    5,6,7,8-tetrahydromethanopterin hydro-lyase
4.2.1.148    2-methylfumaryl-CoA hydratase
4.2.1.149    crotonobetainyl-CoA hydratase
4.2.1.150    short-chain-enoyl-CoA hydratase
4.2.1.151    chorismate dehydratase
4.2.1.152    hydroperoxy icosatetraenoate dehydratase
4.2.1.153    3-methylfumaryl-CoA hydratase
4.2.1.154    tetracenomycin F2 cyclase
4.2.1.155    methylthioacryloyl-CoA hydratase
4.2.1.156    L-talarate dehydratase
4.2.1.157    (R)-2-hydroxyisocaproyl-CoA dehydratase
4.2.1.158    galactarate dehydratase (D-threo-forming)
4.2.1.159    dTDP-4-dehydro-6-deoxy-alpha-D-glucopyranose 2,3-dehydratase
4.2.1.160    2,5-diamino-6-(5-phospho-D-ribosylamino)pyrimidin-4(3H)-one
             isomerase/dehydratase
4.2.1.161    bisanhydrobacterioruberin hydratase
4.2.1.162    6-deoxy-6-sulfo-D-gluconate dehydratase
4.2.1.163    2-oxo-hept-4-ene-1,7-dioate hydratase
4.2.1.164    dTDP-4-dehydro-2,6-dideoxy-D-glucose 3-dehydratase
4.2.1.165    chlorophyllide a 3(1)-hydratase
4.2.1.166    phosphinomethylmalate isomerase
4.2.1.167    (R)-2-hydroxyglutaryl-CoA dehydratase
4.2.1.168    GDP-4-dehydro-6-deoxy-alpha-D-mannose 3-dehydratase
4.2.1.169    3-vinylbacteriochlorophyllide d 3(1)-hydratase
4.2.1.170    2-(omega-methylthio)alkylmalate dehydratase
4.2.1.171    cis-L-3-hydroxyproline dehydratase
4.2.1.172    trans-4-hydroxy-L-proline dehydratase
4.2.1.173    ent-8alpha-hydroxylabd-13-en-15-yl diphosphate synthase
4.2.1.174    peregrinol diphosphate synthase
4.2.1.175    (R)-3-(aryl)lactoyl-CoA dehydratase
4.2.1.176    L-lyxonate dehydratase
4.2.1.177    (2S)-3-sulfopropanediol dehydratase
4.2.1.178    difructose-dianhydride-III synthase
4.2.1.179    difructose-anhydride-I synthase
4.2.1.n1     Transferred entry: 4.2.1.126
4.2.1.n2     Transferred entry: 4.2.1.134